This study aimed to investigate the physiochemical properties of Sarawak's adapted Liberica coffee silverskin (CS) using multiple solvents (distilled water, methanol, and ethanol) its impact on total phenolic content (TPC), flavonoid (TFC), antioxidant activities CS. The results showed that highest TPC was observed in methanol extract (15.24 ± 0.65 mg GAE/g), while TFC recorded when extracted w...

–Abundant as it may seem, in Nigeria, access to clean and potable water is a great challenge. Hence, the reason the physiochemical properties of the groundwater in Agbowo and Ajibode communities in Oyo State, Southwestern Nigeria was analyzed. Water samples were collected from fifteen shallow wells, with varying depths. The water quality parameters were analyzed in accordance to standard method...

We have shown previously that human leukocyte antigen (HLA) immunogenicity, defined by the physiochemical properties of mismatched amino acids, predicts humoral alloimmunity, and now report the effect on long-term graft survival after kidney transplantation. The influence of HLA-A and -B mismatch, number of amino acid mismatches (after interlocus subtraction) and their physiochemical (electrost...

Adequate modeling of mitochondrial sequence evolution is an essential component of mitochondrial phylogenomics (comparative mitogenomics). There is wide recognition within the field that lineage-specific aspects of mitochondrial evolution should be accommodated through lineage-specific amino-acid exchangeability matrices (e.g., mtMam for mammalian data). However, such a matrix must be applied t...

PURPOSE OF REVIEW The immunogenic capacity of donor human leukocyte antigen (HLA) to induce humoral immune responses is not an intrinsic property of the mismatched alloantigen but depends on the HLA phenotype of the recipient. In recent years, advances in molecular sequence technology and information from X-ray crystallography have enabled structural comparison of donor and recipient HLA type p...

Drug-eluting stents have emerged as the most effective method for treating restenosis following percutaneous coronary interventions. This thesis investigates how drugs with similar physiochemical properties but different specific binding targets yield drastically different tissue transport, retention and ultimately efficacy independent of their putative biological effects. Our central hypothesi...

Introduction and Aim. Exceptional properties of the NiTi archwires may be jeopardized by the oral cavity; thus its long-term effect on the mechanical and physiochemical properties of NiTi archwires was the aim of work. Material and Methods. Study group comprised sixty 0.016 × 0.022 NiTi archwires from the same manufacturer evaluated (group A) after the first 12 weeks of orthodontic treatment. 3...

Soil is important among all the components of terrestrial ecosystems and is a main source of production in agriculture. Since soil is a dynamic system there is a continuous reaction between soil minerals, organic matter and organisms. These reactions influences physiochemical and biological properties of soil. Soil phosphatases is one of enzyme which plays a major role in the mineralisation pro...

Target-based approaches for human African trypanosomiasis (HAT) and related parasites can be a valuable route for drug discovery for these diseases. However, care needs to be taken in selection of both the actual drug target and the chemical matter that is developed. In this article, potential criteria to aid target selection are described. Then the physiochemical properties of typical oral dru...