Front Cover. Cancer has become a leading cause of death worldwide, oncology suggests chemotherapeutical drugs based on synthesized anticancer agents, phytomedicine, and metal complexes so far. On this basis, naturally-occurring alkaloids mackinazolinone isaindigotone were as templates target heterocycles, the synthesis tricyclofuran[2,3-d]pyrimidine was studied under scaffold-hopping strategies...

In the contemporary world due to technological development human life has become vulnerable and more at risk because now diseases are complicated. Similarly causative agents, particularly viruses, have complex mutation of their genetic material that results in resistant virulent strains. So counter these a strong immune system is required which can save living body. Since medieval times plants ...

Ayurveda, the system of traditional medicine from India, holds that 'Rasa', a concept roughly corresponding to taste, is a basis for identifying pharmacological properties of plants and other materia medica used in Dravyaguna-its system of phytomedicine. This idea has recently found support in studies of ibuprofen, the pharmacological properties of which are similar to those of oleocanthal, bec...

The gradual transition from the long-standing use of monodrug therapy in classical medicine to the new concept of a multidrug and multitarget therapy has great implications for the research strategies of natural products chemistry and phytomedicine. The rationalization of the new strategies, however, requires great efforts in: standardization of monoand multiphytopreparations using all availabl...