introduction: it is believed that locus coeruleus (lc) influences the sensory information processing. however, its role in cortical surround inhibitory mechanism is not understood. in this experiment, using controlled mechanical displacement of whiskers we investigated the effect of phasic electrical stimulation of lc on response of layer v barrel cortical neurons in anesthetized rat. methods: ...

introduction: systemic application of capsaicin to neonatel rodents depletes their primary afferent c-fibers and also results in a wide variety of changes observable in adulthood. the manual methods used for stimulation of vibrissa provide limited information on response properties of barrel cortical neurons. in this study the effect of c-fiber depletion induced by neonatal capsaicin (cap) trea...

BACKGROUND Water pipe smoking is increasing in Eastern Mediterranean Region. The objective of this study was to investigate any relationship between water pipe smoking and health-related quality of life in the general population of Bandar Abbas, Iran. METHODS Using a multistage sampling method, a random sample of 1675 individuals aged 15 years and over was studied from June through July 2007....

Pipe network layout optimization is an important and difficult problem in pipe network engineering. Differing from the previously proposed approaches for various optimization formulations, the authors use a methodology for pipe network optimization consisting of network layout optimization coupled with pipe sizing analysis. The methodology is based on a novel heuristic optimization algorithm in...

An analytical investigation and conceptual design of a disk-shaped asymmetric heat pipe is presented in this work. Using the conservative formulations for the steady incompressible vapor and liquid flow for a disk-shaped heat pipe, an in-depth integral analysis is applied. Analytical results for the asymmetric vapor velocity profile, the vapor and liquid pressure distributions, and the vapor te...

BACKGROUND Smoking tobacco preparations in a water pipe (hookah) is widespread in many places of the world and is perceived by many as relatively safe. We investigated biomarkers of toxicant exposure with water pipe compared with cigarette smoking. METHODS We conducted a crossover study to assess daily nicotine and carcinogen exposure with water pipe and cigarette smoking in 13 people who wer...

Article history: Received: 18.09.2013. Received in revised form: 21.03.2014. Accepted: 24.03.2014. Static structural analysis of a pipe during laying is usually performed by use of finite element analysis tools specialized for this purpose. In this paper, Abaqus/CAE, which is general purpose FEA software, was used for a static non-linear structural analysis of a pipe during pipe laying. The pip...

BACKGROUND Water pipe tobacco smoking is spreading globally and is increasingly becoming popular in the United States, particularly among young people. Although many perceive water pipe smoking to be relatively safe, clinical experimental studies indicate significant exposures to tobacco smoke carcinogens following water pipe use. We investigated biomarkers of nicotine intake and carcinogen exp...

evaluating existing flexible pavement condition is a pre-requisite to choose improvement technique that has to be adopted to enhance its quality. to evaluate existing pavements, non-destructive testing methods are desirable. benkelman beam and 5th wheel bump integrator are used to conduct non-destructive tests like deflection and roughness surveys on the existing pavement of 4 lane divided carr...

In the present study, heat transfer and entropy analysis for flow through a pipe system is considered. The Reynolds number and the pipe wall temperature effects on entropy distribution and total entropy generation in the pipe are investigated. Numerical scheme employing a control volume approach is introduced when solving the governing equations. Steel is selected as pipe material, while water ...