In an earlier communication, marked changes were reported in the level of nucleic acids during structurally well defined stages in the genesis of crown gall tumors in tomato (9). In view of the distinctive pattern of these changes, it seemed ad visable to extend these studies to other plant tumors to ascertain whether nucleic acid changes were, in fact, concurrent with the process of tumorigene...

The common use of Agrobacterium as a gene vector for plants has somewhat ob-scured the fact that this bacterium remains an important plant pathogen. Pathogenic strainsof the genus Agrobacterium cause unorganized tissue growth called crown gall or profuseabnormal root development called hairy root. Agrobacterium tumefaciens induces galls onroots and crowns of several fruit and fo...

Controlling crown gall in grapevine ( Vitis vinifera L.) caused by the pathogenic bacterium Allorhizobium vitis is a major challenge for global viticulture, as this pathogen highly persistent vineyards once infected. The bacteria can enter plant through open wounds during pruning and then systemically colonize plant. This study aimed at evaluating potential of Paraburkholderia phytofirmans PsJN...

Glioblastoma multiforme (GBM) is one of the most aggressive and malignant forms of brain tumors. Despite recent advances in operative and postoperative treatments, it is almost impossible to perform complete resection of these tumors owing to their invasive and diffuse nature. Several natural plant-derived products, however, have been demonstrated to have promising therapeutic effects, such tha...

cytomegalovirus (cmv) is a widespread pathogen that is found in milk, saliva, urine, cervical secretions, and semen fluid. it is supposed that cmv is a risk factor for breast cancer. the aim of this study was to determine the frequency of cmv among benign and malignant breast tumors. paraffin embedded breast carcinoma (n=24) and fibroadenoma (n=24) samples were collected from toos and firoozgar...

purpose: to report an extremely rare presentation of isolated orbital xanthogranuloma with no systemic disease, nor dermatologic manifestation. case report: the patient was a 45-year-old man complaining of a mass lesion in the superior and inferior eyelids of his right eye; the lesions had been enlarging slowly and painlessly since 5 years before. other examinations (including skin, heart, etc....

abstract objective tumors of the central nervous system constitute the largest group of solid neoplasms in children and are second only to leukemia in their overall frequency during childhood. the main purpose of the present study is to determine the incidence, age, sex, location and histological diagnosis of cns tumors in children, less than 15 years of age, in the mofid children's hospital, i...

intracranial hemangiopericytomas (hpc) are rare vascular tumors. they account for 0.4% of primary central nervous system tumors. hpc is more commonly located supratentorially and tends to occur in a younger age group, with average age at presentation of 38–42 years. the tumor was found throughout the entire cns, usually superficially and closely related to the meninges. moreover, they have a st...

Bean leaf tumors induced by Agrobacterium tumefaciens strain 181 show enhanced growth in response to octopine or lysopine only if one of these compounds is present during the period of tumor induction. Either compound applied during this period results in tumors which subsequently respond to both. The combined action of the bacterium plus octopine or lysopine at induction is proposed to induce ...

Wild-type VirE2 and VirD2 proteins from Agrobacterium tumefaciens contain nuclear targeting sequences (NLS) that are likely involved in directing transferred T strands to the plant nucleus. An A. tumefaciens virE2 virD2DeltaNLS double mutant was able to form tumors on VirE2-producing transgenic tobacco but not on wild-type tobacco. Because this mutant bacterial strain contains no known T-strand...