background platelet rich plasma is known for its hemostatic, adhesive and healing properties in view of the multiple growth factors released from the platelets to the site of wound. the primary objective of this study was to use autologous platelet rich plasma (prp) in wound beds for anchorage of skin grafts instead of conventional methods like sutures, staplers or glue. methods in a single cen...

autologous fat transfer offers many qualities of a ideal soft tissue filler. main advantages of fat grafting ensue from the fact that the lipoaspirate tissue is an abundant source of regenerative pluripotential cells. however, the reported rates of fat cell survival vary greatly in the medical literature (10-90%). different techniques of harvesting, processing, and reinjecting the fat cells are...

background cartilage tissue has limited regenerative capacity and the management of cartilage defects has always been a challenging issue. platelet-rich plasma (prp) has been recently been used to improve healing of cartilage defects. in the present experiment, we aimed to investigate the effects of prp on regeneration capacity as well as survival of the cartilage grafts in a rabbit model. meth...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: the efficacy of mitoxantrone induction therapy in rapidly worsening multiple sclerosis (ms) is well established. plasma exchange is also applied as an adjuvant in exacerbations of relapsing ms. the aim of this study was to compare the efficacy of combination therapy with mitoxantrone and plasma exchange versus ...

background and aims: a selective and sensitive high performance liquid chromatography-electrospray ionization mass spectrometry method has been established for determination of methotrexate in human plasma. methods: methotrexate was extracted from plasma with acetonitrile. the mobile phase consisted of acetonitrile-water-formic acid 74: 25: 1(v/v). twenty µl of sample was chromatographically an...

a chemiluminescence (cl) method has been developed for the determination of hydroxyzine (hyd) and its metabolite cetirizine (cet). the method is based on sensitizing effect of cet and hyd on the weak cl reaction between ru(phen)32+ and acidic ce(iv). a mechanism for the cl reaction has been proposed on the basis of uv-vis, fluorescent and cl spectra. by using the recommended procedure, the cali...

introduction: nowadays the necessity of the existence of a certain width of keratinized gingiva is emphasized upon to maintain periodontal health and prevent soft tissue recession around teeth and dental implants. this study was carried out to compare two gingival graft procedures including connective tissue graft and graft with a combination of collagen sponge with platelet-rich plasma and pla...

a rapid and sensitive hplc method has been developed for the quantification of mirtazapine (mrz), a noradrenergic and specific serotonergic inhibitor antidepressant (nassa) and its two major metabolites n-desmethylmirtazapine (ndm) and 8-hydroxymirtazapine (8-ohm) in human plasma. the separation was achieved using chromolith c18 column and a mobile phase of acetonitrile: phosphate buffer (ph=3,...

osteoporosis is a metabolic disease characterized by reduction in bone density and susceptibility to deformity and fracture. some studies show that osteoblasts can create inter-cellular free radicals that lead to cellular death. superoxide dismutase (sod) plays an essential role in cell defense against reactive oxygen metabolites. the purpose of this study was to measure the plasma sod activiti...

patients and methods seventy patients with chronic partial supraspinatus tears in magnetic resonance imaging were randomized into two groups; prp (n = 35) and pt (n = 35). before the treatment, at the end of the treatment and at the 12th month after the end of the treatment, range of motion (rom), visual analog scale (vas) for pain, disabilities of arm, shoulder and hand questionnaire (dash), n...