The clinical use of PRP therapy in the practical setting of orthopaedic fields is increasing partly because of the accessibility of devices that are used in outpatient preparation and delivery. Another reason is the strong advertisement of PRP procedures as the ultimate treatment and novel technology for knee problems by a few orthopaedic surgeons based on claims of abundant scientific eviden...

Background: Intra-articular injection of Platelet-rich plasma (PRP) is an effective method for the treatment of patientswith knee osteoarthritis (OA). This study aimed to assess the effects of PRP injection on OA, based on gene expressionanalysis.Methods: A sample of 30 subjects with knee OA was asked to complete the Persian versions of the Intermittent andConstant Osteo...

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introduction autologous plasma-rich platelet (prp) is a human platelet concentrated product which is in low volume of plasma. using prp in rejuvenation and resolution of some cosmetic problems has been already popular in many countries and also in iran. as no study performed in this field in iran and regarding the high prevalence of using prp in society with no validate references in the case o...

Background: The purpose of this study was to create biomaterial scaffolds like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) containing stromal cell-derived factor-1 (SDF1) as a chemokine to induce hyaline cartilage regeneration of rabbit knee in a full thickness defect.Methods: We created a full thickness defect in the trochlear groove of thirty-six bilateral knees of eighteen matu...

OBJECTIVE Platelet-rich plasma is blood plasma enriched with platelets and contains various growth factors. Two major issues remain to be resolved in the use of platelet-rich plasma: the short biological activity after application, and the need to prepare platelet-rich plasma at each application instance. To overcome these problems, we developed a drug delivery system using gelatin hydrogel and...

detected. Ii both cases malonic acid was by far the most abundant product. The traces of glutaric and adipic acid in the oxidation products of the C18 and C1,9 acid respectively, can be explained by the presence of C20 and C21 pentaenoic acid, from which the above dicarboxylic acids are the known oxidation products. However, the possible presence of small amounts of an isomeric octadecatetraeno...

Molloy, et. al., (2003) address specific growth factors encountered in ligament and tendon healing. After reading about the factors found in superficial wounds, above, these should appear familiar, including: Platelet derived growth factor (PDGF)—produced shortly after tendon injury, stimulates production of other growth factors such as IGF-1, and is involved in the tissue remodeling phase of h...