نتایج جستجو برای: platinum infiltration

تعداد نتایج: 74302  

2017
Man Xiao Zaiju Huang Jing Cai Jinghui Jia Yuzeng Zhang Weihong Dong Zehua Wang

BACKGROUND Platinum-based agents are widely used in chemotherapy against solid tumors and insufficient intracellular drug accumulation is one of the leading causes of platinum resistance which is associated with poor survival of tumor patients. Thus, the detection of intracellular platinum is pivotal for studies aiming to overcome platinum resistance. In the present study, we aimed to establish...

2015
Dimitra T. Stefanou Aristotelis Bamias Hara Episkopou Soterios A. Kyrtopoulos Maria Likka Theodore Kalampokas Stylianos Photiou Nikos Gavalas Petros P. Sfikakis Meletios A. Dimopoulos Vassilis L. Souliotis

Ovarian carcinoma (OC) is the most lethal gynecological malignancy. Despite the advances in the treatment of OC with combinatorial regimens, including surgery and platinum-based chemotherapy, patients generally exhibit poor prognosis due to high chemotherapy resistance. Herein, we tested the hypothesis that DNA damage response (DDR) pathways are involved in resistance of OC patients to platinum...

Use of the double ring infiltrometer to measure soil water infiltration in center pivot irrigation systems isn’t an accurate approach because the real conditions of infiltration under center pivot sprinklers is different from what happens in the double ring. In this study the infiltration parameters were evaluated in real conditions of a center pivot system. For this purpose a single ring...

حقی زاده, علی, زینی وند, حسین, سلیمانی, لیلا,

The process of infiltration is one of the most important components of the hydrological cycle. On the other hand, the direct measurement of infiltration process is difficult, time spending and expensive. Infiltration models play a main role in managing water resources. Therefore, different types of models with various degrees of complexity were developed to reach this aim.  So, this research ca...

2015
Hisao Imai Kyoichi Kaira Keita Mori Akira Ono Hiroaki Akamatsu Tetsuhiko Taira Reiko Yoshino Hirotsugu Kenmotsu Jun-ichi Saitoh Hideyuki Harada Tateaki Naito Haruyasu Murakami Yoshio Tomizawa Masana Matsuura Ryusei Saito Takashi Nakajima Masanobu Yamada Toshiaki Takahashi

Platinum-based chemoradiotherapy (CRT) is a standard front-line treatment for locally advanced non-small cell lung cancer (NSCLC). However, no clinical trials have compared the efficacy and toxicity of platinum combination and docetaxel as subsequent re-challenge chemotherapies after cancer recurrence following CRT. This study aimed to evaluate the efficacy and toxicity of platinum combination ...

2006
Alan J. Kraker Charles W. Moore

Three murine leukemia lines resistant to cÃo-diamminedichloroplatinum(II) and one line resistant to diaminocyclohexane (DACH) platinum(II) complexes were compared to their platinum-sensitive parent lines to determine whether differences in net platinum accumulation were related to the resistant phenotype. The ciVdiamminedichloroplatinum(II}-resistant lines (L1210PIR4, L1210DDPS, P388PtR4) and t...

2017
Marije Risselada Keith E Linder Emily Griffith Brittney V Roberts Gigi Davidson William C Zamboni Kristen M Messenger

The objectives of this study were to assess the pharmacokinetics and safety of subcutaneously delivered carboplatin in poloxamer 407 in rats. Carboplatin (5mg/rat) in 0.5ml poloxamer 407 (1.0 ml total volume) was administered subcutaneously in a right subcutaneous perineal incision in all 12 treatment rats. Three control rats received 1.0 ml of poloxamer 407. Total platinum was measured in plas...

1988
A. G. Sykes

Reactions of Complexes of Platinum Metals with Bio-Molecules Water Soluble Rhodium Catalysts The Destruction of Polychlorinated Biphenyls Chemical Conversion of Carbon Dioxide The Electrodeposition of Platinum and Platinum Alloys Ruthenium in Cancer Chemotherapy Lean-Burn Oxygen Sensor Material Control of Corrosion in Molten Carbonate Fuel Cells Flammable Gas Detection International Congress on...

Journal: :Nano letters 2005
Xiaozhong Ji Anthony Zuppero Jawahar M Gidwani Gabor A Somorjai

Forty microampere current was generated on a platinum-titanium dioxide Schottky diode during the platinum catalyzed steady-state oxidation of carbon monoxide at 80 degrees C. For reaction events that produced four CO(2) molecules, three injected electrons were collected in a diode comprising a 5 nm thick platinum and a 150 nm titanium dioxide film. The electron injection flux depends on the thi...

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