Background: Primitive neuroectodermal tumor (PNET) is a rare aggressive type of sarcoma characterized by translocation involving the EWS gene. Peripheral PNET is rarely observed in female breast. So far, only 11 cases of PNETs of breast have been reported in literatures, and no Chinese case has ever been reported. We presented, here, a case of primary PNET of breast occurred in a 32-year-old Ch...

We conducted a matched case-control study to investigate risk factors for the two most common types of brain tumors in children, astrocytic glioma and primitive neuroectodermal tumor (PNET). Since the study focused on gestational exposures, we restricted it to young children because these exposures would be expected to act early in life. Parents of 155 astrocytic glioma cases, 166 PNET cases, a...

Primary primitive neuroectodermal tumors (PNET) are rare malignant tumors, affecting mostly children and adolescents. Only three cases of primary breast PNETs have been reported in the medical literature, with none in Korea. We present a case of a primary PNET of the breast in a 33-year-old woman, with imaging and immunohistopathology findings.

A 48-year-old female patient underwent splenopancreasectomy for a 4-cm pancreatic neuroendocrine tumor (pNET), grade G2, located in the pancreatic tail. One year after surgery, the patient presented an increased serum level of the tumor marker chromogranin A (value: 160 U/l). Therefore, she underwent somatostatin receptor PET/CT using gallium-68DOTATOC for restaging. This imaging method showed ...

OBJECT Primitive neuroectodermal tumors of the central nervous system (CNS-PNET) arising in the brainstem are extremely rare, and knowledge about them is limited. The few existing case series report fatal outcomes. The purpose of this study was to analyze clinical characteristics of and outcome for brainstem CNS-PNET patients treated according to the consecutive, population-based HIT studies co...

Les tumeurs neuroectodermiques primitives (PNET) mésentériques sont exceptionnelles. Elles appartiennent au groupe des tumeurs neuroectodermiques primitives périphériques et sont assimilées histologiquement aux sarcomes d'Ewing. Le diagnostic repose essentiellement sur les résultats immunohistochimiques et cytogénétiques. Nous nous proposons, à travers un cas de PNET à localisation mésentérique...

Primitive neuroectodermal tumor (PNET) is anundifferentiated neoplasm arising from the germinal matrix of the primitive neural tube. It is predominantly an infratentorial tumor of childhood. Adult supratentorial PNETs are less common and extraneural metastasis are extremely unusual. Only five sporadic cases were reported in the international literature.1–6 In this article, we report a rare case...

AIM Advanced pancreatic neuroendocrine tumor (PNET) presents a therapeutic challenge as many are unresectable and relatively resistant to systemic therapy with a high malignant potential. We share our experience using concurrent capecitabine or infusional 5-fluorouracil with radiation for patients with resected and locally advanced PNET. PATIENTS AND METHODS Six patients (two females, four ma...

Connexins (Cxs) are building unit proteins of gap junctions (GJs) that are prognostic markers in carcinomas. To investigate the role of Cx in Ewing sarcoma (EWS)/primitive neuroectodermal tumor (PNET), we examined the expression of Cx43 and Cx26 in 36 EWS/PNETs and found (1) cytoplasmic Cx43 reactivity in 28/36 (78%) cases. (2) Cx43 score was significantly correlated with overall survival (P = ...

Purpose: The aim of this study was to evaluate tne effect the risk group on clinical features disease, treatment strategies and especially survival in children with Non-Wilms’ renal tumors (NWRTs). 
 Materials Methods: Patients diagnosed NWRTs followed up treated between January 2012 2022 were included (n=29; 16 boys 13 girls). They categorized into high- low-risk groups based their histol...