نتایج جستجو برای: poems
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We report a case of POEMS syndrome which relapsed six years after autologous peripheral blood stem cell transplantation. According to encouraging data published recently, we treated the patient with cyclophosphamide, dexamethasone and the VEGF-antibody bevacizumab. After an initial improvement, the subsequent course was complicated by severe adverse events leading to multiorgan failure and deat...
Polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes (POEMS) syndrome is a rare paraneoplastic disorder associated with an underlying plasma cell dyscrasia and multiorgan failure. POEMS syndrome is potentially fatal and adversely affects quality of life. Oedema is common with many patients affected by pleural effusions, ascites and lower limb oedema. Bioelectrical impedance ...
POEMS syndrome is a rare paraneoplastic syndrome that is caused by an underlying plasma cell disorder. Its main features include polyradiculoneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes. Other important characteristics of POEMS include papilledema, extravascular volume overload, sclerotic bone lesions, and thrombocytosis/erythrocytosis (PEST). Vasc...
Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes (POEMS) syndrome is a systemic condition related to plasma cell dyscrasia. Increased vascular permeability is responsible for some of the hallmarks of this disorder that may include renal microangiopathy. Several lines of evidence suggest that vascular endothelial growth factor (VEGF) is central to the pathogenesis o...
Editor’s note for authors of submissions to Pectoriloquy: Poems should not exceed 350 words, should not have been previously published, and should be related to concerns of physicians and medicine. First submissions to the Pectoriloquy Section should be submitted via e-mail to [email protected] . Authors of accepted poems will be asked to submit the fi nal version to CHEST Manuscript Central....
POEMS syndrome is a clinical unit with a very heterogenous clinical behavior. Its diagnostics as well as monitoring are not easy and depend on clinician ́s experience. We present three case reports of patients with POEMS syndrome with different clinical manifestation and course of the disease. Our presentation demonstrates the benefit of the use of biochemical parameter VEGF (vascular endothelia...
INTRODUCTION Polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes (POEMS) syndrome is a fatal systemic disorder associated with plasma cell dyscrasia and the overproduction of the vascular endothelial growth factor (VEGF). Recently, the prognosis of POEMS was substantially improved by introduction of therapeutic intervention for myeloma. However, no randomised clinical trial...
Computational analysis of poetry is a challenging and interesting task in NLP. Human expertise on stylistics and aesthetics of poetry is generally expensive and scarce. In this work, we delve into the data to automatically extract stylistic and linguistic information which are useful for analysis and comparison of poems. We make use of semantic (word) features to perform subject-based classific...
In most cases, there is only one cause for a patient’s peripheral neuropathy (e.g. diabetes mellitus, uremia, inflammatory demyelination, vasculitic, inherited or other). However, occasionally more than one cause may be present and clinically important. The case illustrated here shows that inherited (CMT1A) and acquired (POEMS) demyelinating neuropathies can coexist and both contribute to the c...
POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome is a rare paraneoplastic syndrome elicited by plasma cell dyscrasia. Its clinical manifestations are multiple and stroke is not a recognized feature. A 44-year-old woman with a 3-month history of bilateral lower extremity sensorimotor disturbance was admitted to our hospital. Examinations reve...
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