نتایج جستجو برای: point mutation

تعداد نتایج: 796715  

Journal: :The Journal of Thoracic and Cardiovascular Surgery 1992

Hamid Abdollahi, Mehdi Hayatbakhsh Abasi Mohammad Javad Zahedi Mohammad Savari Sodaif Darvish Moghadam

Background: Clarithromycin resistance in Helicbacter pylori has been found to be associated with point mutations in 23s rRNA gene leads to reduced affinity of the antibiotic to its ribosomal target or changing the site of methylation. The aim of this study was to determine the most important point mutations in 23s rRNA gene in H. pylori that are closely related to clarith-romycin resistance amo...

Journal: :PLoS Computational Biology 2007
Lawrence C. Lee Florence Horn Fred E. Cohen

Protein point mutations are an essential component of the evolutionary and experimental analysis of protein structure and function. While many manually curated databases attempt to index point mutations, most experimentally generated point mutations and the biological impacts of the changes are described in the peer-reviewed published literature. We describe an application, Mutation GraB (Graph...

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