There are two possible contributions to the heterogeneity of mucus glycoproteins as observed in the analytical ultracentrifuge: firstly, from associative phenomena, and, secondly, from a polydisperse distribution of non-interacting species of different molecular masses. It is shown from the non-superposability of plots of point-weightaverage relative molecular masses against concentration for d...

The objective of this study was formulation and evaluation of mucoadhesive nanoparticles of acyclovir. Nanoparticles were prepared by one step desolvation method by using gelatin as a mucoadhesive polymer. The effects of amount of gelatin and Pluronic F-68 on particle size, polydispersity index, entrapment efficiency, loading efficiency, mucoadhesive strength were studied. Nanoparticulate formu...

In a system of N particles, with continuous size polydispersity there exists N(N-1) number partial structure factors making it analytically less tractable. A common practice is to treat the as an effective one component which known exhibit artificial softening structure. The aim this study describe in terms M pseudo species such that we can avoid but at same time have value << N. We use potenti...

– We study the probability, PS(t), of a cluster to remain intact in one-dimensional cluster-cluster aggregation when the cluster diffusion coefficient scales with size as D(s) ∼ s . PS(t) exhibits a stretched exponential decay for γ < 0 and the power laws t −3/2 for γ = 0, and t−2/(2−γ) for 0 < γ < 2. A random walk picture explains the discontinuous and non-monotonic behavior of the exponent. T...

2014 We consider a linear polymer melt where the chains are made by condensation of bifunctional monomers. In the very large distribution of molecular weights that is obtained one may distinguish typical and very large chains with different behaviours. Screening is effective in the former, which act as a (good) solvent for the latter. The cross-over molecular weight N * between the two classes ...

Heparin proteoglycan formed by incubation of purified rat peritoneal mast cells with [3KS]sulfate has previously been shown to be a proteoglycan with an approximate average molecular weight of 750,000 by gel filtration. This proteoglycan which was isolated in the absence of proteases has now been shown to contain approximately equal amounts of serine and glycine which together account for 82% o...