In contrast to mycoplasma virus L1 and L2 circular DNA, mycoplasma virus L3 linear DNA is not biologically active in polyethylene glycol-mediated transfection. Electroporation of Acholeplasma laidlawii, however, leads to plaque formation after incubation with L3 DNA. The efficiency of electroporation-mediated transfection is 1/10 that of polyethylene glycol-mediated transfection as estimated wi...

background: there are many preparation regimens for bowel cleansing. given their adverse effects, none of them have been considered perfect by the endoscopists. the aim of this study was to compare the effects of two bowel cleansing regimens on clean colonic preparation the subjects'well being and electrolyte balance. materials andmethods: atotal number of 280 patients were randomly assigned to...

long-chain diacrylate crosslinkers based on linear α,ω-diols were synthesized and characterized using ftir and 1h nmr spectroscopy. the highest reaction yield (99.5%) was due to polyethylene glycol diacrylate 1000 (pegda-1000). then, kaolin-containing poly(potassium acrylate-acrylic acid) superabsorbent composites and kaolin-free counterparts were synthesized using pegda-1000.the effect of the ...

UNLABELLED ABSTRACT QUESTION: I have come across many pediatric patients with functional constipation. Is polyethylene glycol 3350 without electrolytes a safe and effective long-term treatment option for these patients? ANSWER Functional constipation is a common and often difficult problem for parents and families to deal with. Polyethylene glycol 3350 is a safe and effective long-term laxati...

Surfaces covered with polyethylene glycol (PEG; HO-(CH(2)-CH(2)-O)(n)-H) have been shown to be biocompatible because PEG's properties yield nonimmunogenicity, nonantigenicity, and protein rejection. To produce a biocompatible surface coating, we have developed a method for grafting PEG onto activated silica films. We first deposited an amorphous silica film by plasma-enhanced chemical vapor dep...

Covalent attachment of polyethylene glycol (PEG) to active proteins (PEGylation technology) successfully generated several FDA-approved compounds, including four blockbusters, which are considered non immunogenic. However, PEG antibodies and intolerance to the infusion were reported in some patients with gout treated with pegloticase, a PEG-uricase recently approved by the FDA (Food and Drug Ad...

Streaming of gastrointestinal contents depends on the demonstration of differential rates of recovery of equal doses of two synchronously fed markers. There was no significant difference in the rate of throughput of polyethylene glycol (a liquid phase marker) and chromium sesquioxide (a solid phase marker) in healthy volunteers (n = 7) and hospital inpatients (n = 5) with normal bowel habit, so...

Thermophoresis, the Soret effect, depletes a high concentration of a polyethylene glycol polymer solution from the hot region and builds a concentration gradient. In such a solution, solutes of small concentration experience thermophoresis and polyethylene glycol concentration-dependent restoring forces. We report that by using focused laser heating and varying the polyethylene glycol concentra...

In the present work, gliclazide loaded polyethylene glycol (PEG) based solid dispersions were prepared using fusion method in order to improve the solubility and dissolution rate of gliclazide. The compatibility of the drug with various formulation components was established. Solid dispersions (SDs) of gliclazide and polyethylene glycol (PEG 4000, 6000 and 8000) at three mass ratios (1:1, 1:3, ...