UNIM-352, a polyherbal preparation used in the traditional Unani system of medicine for bronchial asthma. The present study evaluated the possible effects of UNIM-352 on biochemical markers and structural changes in allergen induced airway-remodelling in rats. Wistar rats were immunized on day 1 with ovalbumin and Al(OH)3 and challenged with aerosolized ovalbumin from day 15 to 21. They were th...

The objective of present study was to develop and validate a dissolution test for polyherbal hepatoprotective tablets containing andrographolide with bio-relevant media. Different dissolution conditions such as basket (type I)/paddle (type II) agitation, rotation speed, dissolution medium and volume were evaluated. The dissolution samples were analyzed and validated using a high-performance liq...

The present study was carried out to evaluate the effect of polyherbal formulation (DiarunPlus) on the blood glucose changes and nociceptive threshold and tolerance on non-diabetic mice (which rendered hyperglycemic with exogenous administration of dextrose). This study was carried in 2 phases, during phase-I, the mice were rendered hyperglycemic by repeated injections of dextrose (2g/kg i.p.) ...

AIMS/BACKGROUND This study was to investigated the synergistic effect of polyherbal formulations (PHF) of Allium sativum L., Eugenia jambolana Lam., Momordica charantia L., Ocimum sanctum Linn., and Psidium guajava L. in the inhibition/induction of hepatic and intestinal cytochrome P450 (CYPs) and Phase-II conjugated drug metabolizing enzymes (DMEs). Consumption of these herbal remedy has been ...

The present investigation was an attempt to evaluate the anti-inflammatory effect of a polyherbal preparation (Sudarshanam Oil) on hematological parameters in Wistar rats. This polyherbal formula contains main ingredients of Tinaspora Cordifolia, Curcuma longa, Terminalia chebula, Emblica officinalis, Andrographis paniculata and Terminalia belerica. The active phytochemicals such as tannins, gl...