The use of polymeric nanoparticles, especially those composed of natural polymers, has become a very interesting approach in drug delivery, mainly because of the advantages offered by their small dimensions. The aim of this work was to develop a novel formulation of nanoparticles comprised of two natural marine-derived polymers, namely chitosan and carrageenan, and to evaluate their potential f...

Biodegradable polymeric nanoparticles: An overview - IJPP- Print ISSN No: 2393-9079 Online No:- 2393-9087 Article DOI 10.18231/j.ijpp.2022.025, Indian Journal of Pharmacy and Pharmacology-Indian J Pharm Pharmacol

We have found that not only block copolymers but also ionomers can self-assemble in a selective solvent to form surfactant-free nanoparticles. The self-assembly can be induced by chemical reaction, polymer-polymer complexation, and microphase inversion in addition to the temperature. A recently developed microwave method for the preparation of uniform surfactant-free polymeric nanoparticles is ...

RBC membrane-cloaked polymeric nanoparticles represent an emerging nanocarrier platform with extended circulation in vivo. A lipid-insertion method is employed to functionalize these nanoparticles without the need for direct chemical conjugation. Insertion of both folate and the nucleolin-targeting aptamer AS1411 shows receptor-specific targeting against model cancer cell lines.

Polymeric micelles and shell crosslinked knedel-like (SCK) nanoparticles were loaded with up to 48% (w/w) cisplatin. These spherical cisplatin-loaded nanoparticles displayed sustained platinum release over 5 days in PBS, enhanced stability over free cisplatin in aqueous milieu, and significant antitumor activity in vitro against two cancer cell lines.

A precise control of metallic-nanoparticle assembly is highly critical for the realization of tangible, high-performance devices or materials. Until recently, nanoparticle assembly using 1D templates had been limited to a narrow spectrum of nanoparticles as it was mostly dependent on the surface chemistry of the nanoparticles used. Inspired by the universal adhesive properties of mussels, we de...