A REVIEW of the remarkable polymorphism in the European land snail Cepaea nemoralis L. and of the various interpretations based on it has been given in a previous issue of this journal (CAIN and SHEPPARD 1954). Since the adaptive and evolutionary significance of the polymorphism is the subject of active research, a considerably better knowledge of its genetics is desirable. Subsequently, LAMOTT...

OBJECTIVES North Africa has a complex demographic history of migrations from within Africa, Europe, and the Middle East. However, population genetic studies, especially for autosomal genetic markers, are few relative to other world regions. We examined autosomal markers for eight Tunisian and Libyan populations in order to place them in a global context. MATERIALS AND METHODS Data were collec...

BACKGROUND Linkage with 18p11 is one of the replicated findings in molecular genetics of bipolar disorder. Because mitochondrial dysfunction has been suggested in bipolar disorder, NDUFV2 at 18p11, encoding a subunit of the complex I, reduced nicotinamide adenine dinucleotide (NADH)ubiquinone oxidoreductase, is a candidate gene for this disorder. We previously reported that a polymorphism in th...

A polymorphism modulating innate immunity signal transduction has recently been shown to influence human susceptibility to many different infections, providing one more indication of the potential of host genetics to reveal physiological pathways and mechanisms that influence resistance to infectious diseases.

BACKGROUND The aim of this study was to examine the association between the MAOA-uVNTR gene polymorphism in a homogeneous subgroups of patients with alcohol dependence categorized according to Lesch's typology. METHODS DNA was provided from alcohol dependent (AD) patients (n=370) and healthy control subjects (n=168) all of Polish descent. The history of alcoholism was obtained using the Polis...

Genetics highlights relationships between biological systems, and as the number of defined osteoarthritis susceptibility alleles increases, there is the natural tendency to assess whether the alleles influence other musculoskeletal phenotypes. That has proven to be the case for the GDF5 polymorphism rs143383, a risk factor for knee osteoarthritis and several other common conditions, including l...

There is a long tradition in population genetics of exploring the maintenance of variation under migration-selection balance using deterministic models that assume infinite population size. With finite population size, stochastic dynamics can greatly reduce the potential for the maintenance of polymorphism, but this has yet to be explored in detail. Here, classical two-patch models are extended...

With large-scale genomic data becoming the norm in biological studies, the storing, integrating, viewing and searching of such data have become a major challenge. In this article, we describe the development of an Arabidopsis thaliana database that hosts the geographic information and genetic polymorphism data for over 6000 accessions and genome-wide association study (GWAS) results for 107 phe...

Received: 12 Sept. 2014, Revised 22 Sept. 2014, Accepted 24 Sept. 2014, Available Online 10 Oct. 2014 Celal Bayar University, School of Medicine, Department of Obstetrics and Gynecology, Manisa, Turkey Celal Bayar University, School of Medicine, Department of Genetics, Manisa, Turkey *Corresponding Author: Burcu Artunc Ulkumen E-mail: [email protected] 1984A/G adrenomedullin (rs3814700) ge...

Zaprionus indianus (fig fly) is a drosophilid of African origin that was recorded in Brazilian territory 1999, quickly dispersing throughout the country, causing impacts on fig culture, and becoming one dominant Drosophilidae species Cerrado biome. Due to fact it an invasive potential pest fruit cultivars, essential monitor variations populations this aiming verify its genetic demographic struc...