pomegranate (punica granatum l.) is an important iranian-native fruit, whose many varieties are cultivated. fruits are widely consumed fresh and in processed forms as juice, jams and etc. pomegranate peel, as a by-product of the commercial juice industry, is a rich source of bioactive compounds. this research has been done to evaluate and compare physical characteristics, total phenolics, total...

The present study aimed to investigate the possible protective effect of olive leaf extract (OLE) and pomegranate peel extract (PPE) against oxytetracycline (OTC)-induced hepatotoxicity in albino rats. The ethanolic extracts of olive leaf and pomegranate peel were screened for evaluating their free radical scavenging properties and total phenolic contents. They have a great antioxidant activity...

BACKGROUND The aim of this study was to explore the mechanism by which cervical cancer is inhibited by promoting IGFBP7 expression using ellagic acid from pomegranate peel extract. MATERIAL AND METHODS HeLa cells were divided into 6 groups: control group (NC), blank control group (BL), and IGFBP7 overexpression group (IGFBP7), and 2.5 uM, 5. 0 uM, and 10.0 uM ellagic acid-treated groups. The ce...

BACKGROUND Azoxymethane (AOM) is a potent carcinogenic agent commonly used to induce colon cancer in rats; the cytotoxicity of AOM is considered to mediate oxidative stress. This study investigated the chemopreventive effect of three natural extracts [pomegranate peel extract (PomPE), papaya peel extract (PapPE) and seaweed extract (SE)] against AOM-induced oxidative stress and carcinogenesis i...

From value-addition viewpoint, the aim of this study was to evaluate the stability of antioxidant capacity of pomegranate fruit co-products in different solvent extracts using the FRAP, DPPH ̇ and ABTS ̇+ assays during in vitro digestion. Antioxidant capacity in the investigated assays were in the order of peel > marc > juice throughout the in vitro digestion irrespective of the extraction solven...

High blood pressure, or "hypertension," is associated with high levels of oxidative stress in the paraventricular nucleus of the hypothalamus. While pomegranate extract is a known antioxidant that is thought to have antihypertensive effects, the mechanism whereby pomegranate extract lowers blood pressure and the tissue that mediates its antihypertensive effects are currently unknown. We have us...