Spanning 30 years and 40 individual videogames across a range of platforms, Pac-Man is one of the most recognizable of all videogame characters and a pop–culture icon. In spite of its widespread popularity, the game receives little sustained academic engagement or analysis. In an attempt to address this, the paper argues that in its classic iterations PacMan generates complex notions of space a...

Paralinguistics organizers such as parenthesis, footnotes, and pop-up fields on screen, should play an important role signalling the writer’s “minimization” intention when secondary points are concerned. This experiment investigated the role of pop-up fields compared to brackets in an information retrieval task. The results showed that, in this kind of task, putting secondary pieces of informat...

INTRODUCTION Pelvic organ prolapse (POP) is a significant public health problem in developing countries including Ethiopia. However, less has been documented on risk factors of POP. Therefore, the aim of this study was to identify the determinants factors of POP. METHODS An unmatched case-control study was conducted among gynecologic patients in Bahir Dar city, North West Ethiopia, from July ...

BACKGROUND There is no consensus on the relationship between depressive symptoms (DS) and pelvic organ prolapse (POP) symptoms and quality of life (QoL). Our hypothesis was that women with DS and POP have worse symptoms and QoL than those without DS and POP. AIM Our aim was to compare two groups of POP patients, those with depressive symptoms and those without, and evaluate the association of...

PURPOSE To validate Gaussian mixture-model with expectation maximization (GEM) and variational Bayesian independent component analysis mixture-models (VIM) for detecting glaucomatous progression along visual field (VF) defect patterns (GEM-progression of patterns (POP) and VIM-POP). To compare GEM-POP and VIM-POP with other methods. METHODS GEM and VIM models separated cross-sectional abnorma...

OBJECTIVE The aims of this study are to detect levels of AGEs and RAGE and SNPs for RAGE in vaginal tissues of women with POP and rats in a repair location, and to explore the relationship between AGEs-RAGE pathway and POP. METHODS This study involved human vaginal tissues in fornix from 44 women with POP and 46 women without POP who were assigned to pelvic floor reconstruction or LAVH. The p...

Continued on page 10 BACKGROUND INFORMATION Pelvic organ prolapse (POP) is uncommon in young women. Most of the 400,000 procedures performed annually in the United States for POP correction are done in perior postmenopausal women (1). Traditionally, most cases of POP are thought to be secondary to damage to the pelvic floor tissues during childbirth and the resulting changes with aging and time...

An Al(porphyrin) functionalized with a large axial ligand was incorporated into a porous organic polymer (POP) using a cobalt-catalyzed acetylene trimerization strategy. Removal of the axial ligand afforded a microporous POP that is catalytically active in the methanolysis of a nerve agent simulant. Supercritical CO2 processing of the POP dramatically increased the pore size and volume, allowin...

-Catenins are conserved regulators of metazoan development that function with TCF DNA-binding proteins to activate transcription. In Caenorhabditis elegans, SYS-1/ -catenin and POP-1/TCF regulate several asymmetric divisions, including that of the somatic gonadal precursor cell (SGP). In the distal but not the proximal SGP daughter, SYS-1/ -catenin and POP-1/TCF transcriptionally activate ceh-2...

BACKGROUND Pelvic organ prolapse (POP) is a common gynecological condition that can affect quality of life (QOL) in women. In Nepal, the prevalence of POP is high, but many affected women are still deprived of treatment. Vaginal hysterectomy with pelvic floor repair is one of the common treatment options for advanced POP. However, QOL outcomes after surgery have not been reported in low-income ...