parathyroid hormone-related protein producing pancreatic neuroendocrine tumors have been infrequently reported. herein, we report a case of an iranian woman who had such a tumor during pregnancy, and gave birth to a female neonate with esophago-tracheal fistula and imperforated anus. hypercalcemia was diagnosed at postpartum because of elevated serum calcium levels in the neonate and neurologic...

retinal pigment epithelium is responsible for maintaining the structural integrity of the retina by an efficient defense against free radicals, photo-oxidative exposure and light energy. for this purpose the main rpe line of defense is melanosomes. melanin content of retinal pigment epithelium cells in adults and neonates reveals remarkable variations. in the current study we compared melanogen...

Background: The Neonatal Resuscitation Program highlights the importance of a newborn's first minute, "Golden Minute", during which pediatrician determines if newborn requires, and initiates advanced resuscitation. From birth to neonatal evaluation, we detect periods that call "Lost Time", delay resuscitation because it is not controlled: "adequate position" in gynecologists must "pass" pediatr...

Introduction: Upper airway distress associated with craniofacial anomaly has been reported widely. An antenatal scan of should alert the attending team to prepare for respiratory in any neonate following delivery. Additionally, a stepwise algorithm is imperative manage difficult children anomalies. Aim: To outline case newborn anomaly. Case study: A premature neonate, born at 36 weeks, was refe...

A neonate with severe oligo-anuric renal failure during multi-organ failure survived with prolonged renal replacement therapy Sir, Here, we report a neonate with severe oligo-anuric renal failure during multi-organ failure who survived with prolonged renal replacement therapy. A female neonate, born at a gestational age of 39 weeks and 3 days, weighing 2780 gram, presented cyanosis on Day 15. S...

We report the anaesthetic management of a mother, and airway management of a neonate with a prenatal diagnosis of cervical cystic hygroma causing upper airway obstruction. The mortality of such neonates due to upper airway obstruction is reported to exceed 20% following deliveries. Elective Caesarean section was performed under general anaesthesia, and in utero tracheal intubation of the neonat...

In adults, psychological stress regulates immune responsiveness in part via the increased levels of corticosterone that are produced as a result of hypothalamic-pituitary-adrenal (HPA) axis activation. However, there is a lack of knowledge as to the role such regulation may play in the neonate. Neonates are severely compromised in their ability to generate an immune response to pathogens encoun...

Transplacental transmission of rubella virus leads to Congenital Rubella Syndrome. It is comprised of congenital cardiac defects (most commonly patent ductus arteriosus), cataracts and sensorineural hearing loss. While prematurity and intra uterine growth retardation are frequent accompaniments of congenital rubella syndrome, at times birth weight can be normal. The possibility of fetal anomali...