This note describes a Bayesian model selection or optimization procedure for post hoc inferences about reduced versions of a full model. The scheme provides the evidence (marginal likelihood) for any reduced model as a function of the posterior density over the parameters of the full model. It rests upon specifying models through priors on their parameters, under the assumption that the likelih...

INTRODUCTION A clinical suspicion of infection is mandatory for diagnosing sepsis in patients with a systemic inflammatory response syndrome. Yet, the accuracy of categorizing critically ill patients presenting to the intensive care unit (ICU) as being infected or not is unknown. We therefore assessed the likelihood of infection in patients who were treated for sepsis upon admission to the ICU,...

Perampanel (PER) is a novel noncompetitive AMPA-receptor antagonist approved in over 40 countries for treatment of partial seizures. The safety and tolerability of PER have been well-documented in three double-blind, randomized, placebo (PBO)-controlled Phase III studies and an open-label extension (OLE). This post hoc analysis evaluated the occurrence and characteristics of the most common tre...

This research study investigates the impact of three sorts of simplification of reading comprehension passages through translating, paraphrasing and elaborating new words and expressions on the Iranian language teaching freshmen's reading comprehension ability. In phase one six English reading pas- sages in one of three types- (a) translated, (b) paraphrased, (c) elaborated words and expression...

Neural networks for NLP are becoming increasingly complex and widespread, there is a growing concern if these models responsible to use. Explaining helps address the safety ethical concerns essential accountability. Interpretability serves provide explanations in terms that understandable humans. Additionally, post-hoc methods after model learned generally model-agnostic. This survey provides c...

English for Specific Academic Purposes (ESAP) uses the results of needs analysis for curriculum development and materials production. ESAP courses should be based on students’ academic needs. Consequently, the present study investigated the English language needs of Iranian undergraduate students of Law. Participants included 218 undergraduate students, 33 graduate students, and 10 content teac...

Abstract Optical character recognition (OCR) is crucial for a deeper access to historical collections. OCR needs account orthographic variations, typefaces, or language evolution (i.e., new letters, word spellings), as the main source of character, word, segmentation transcription errors. For digital corpora prints, errors are further exacerbated due low scan quality and lack standardization. t...

Post hoc analyses from the B-type natriuretic peptide for Acute Shortness of Breath Evaluation (BASEL)-II-ICU study suggest an association between beta-blocker usage at admission and improved mortality in patients treated in the intensive care unit for acute respiratory failure. Although this evidence is encouraging, there is a need for a phase 2 proof-of-concept randomized controlled trial of ...

BACKGROUND Many large-scale clinical studies appear to be interpreted with bias and with hindsight. To select the best treatment, accurate evaluation of randomized controlled trials (RCTs) and fair comparison of the results using the concept of evidence-based medicine are critical. A scoring system has been developed to rate the scientific strength of evidence and thereby provide guidance for b...