BACKGROUND Currently, there is no ideal agent to prevent adhesion formation. We have shown that sildenafil, a phosphodiesterase-5 (PDE-5) inhibitor, reduces post-operative adhesion formation by vasodilatation and increases fibrinolytic activity. Here, we evaluated whether tadalafil, a long-acting PDE-5 inhibitor, decreases post-operative adhesion reformation in rats. MATERIALS AND METHODS Sta...

Objective To evaluate if improvement of laparoscopic skills can reduce postoperative peritoneal adhesion formation in a clinical setting. Study Design We retrospectively evaluated 25 women who underwent laparoscopic myomectomy from January 1993 to June 1994 and 22 women who underwent laparoscopic myomectomy from March 2002 to November 2004. Women had one to four subserous/intramural myomas an...

Background: The fundamentals in the treatment of acute peritonitis include resuscitation, treatment of septicemia, control of the contaminating source and peritoneal toilet. Numerous studies have shown the roles of different solutions such as normal saline, antibiotics and betadine as intraperitoneal lavage, in reducing morbidity and mortality of peritonitis. The objective of this study was to ...

Hysteroscopic complications are infrequent. Major complications include: 1. Uterine perforation that is the most common complication of operative hysteroscopy (0.8 - 1.6 %). The perforation rate is less during diagnostic hysteroscopy. 2. Bowel or bladder injury which is rare, but may occur in association with uterine perforation or as a result of use of electrical current. 3. Cervical laceratio...

BACKGROUND Amitriptyline, a tricyclic antidepressant and potent use-dependent blocker of sodium channels, has been shown to attenuate acute and chronic pain in several preclinical modes. The purpose of this study was to investigate whether intrathecal pretreatment with amitriptyline combined with post-injury intra-peritoneal amitriptyline is more effective than post-injury treatment alone on L5...

surgery to remove some part of the inner ear is an effective intervention to relieve of symptoms. an informed care can decline the patient's fears, and also a pre-operating patient education can facilitate the patient’s recovery. patients, who are in a labyrinthectomy waiting list, feel a combination of anxiety and release. they have spent lots of time to find a treatment for their severe ...

introduction: antibiotic therapy before or after orthognathic surgery is commonly recommended by surgeons to minimize the risk of wound infection. this article evaluates the value of prophylactic antibiotic therapy in order to diminish the incidence of postoperative wound infection after orthognathic surgery.   materials and methods: fifty candidates for bimaxillary orthognathic surgery were di...

BACKGROUND The inevitable post-inflammatory fibrosis and adhesion often compromises future treatment in peritoneal dialysis patients. Here, we describe a patient who experienced an unusual form of peritoneal adhesion that made her give up peritoneal dialysis. However, its unique pattern also saved her from infection caused by bowel perforation. CASE PRESENTATION The female patient discontinue...

BACKGROUND Post-operative peritoneal adhesions are common and serious complications for modern medicine. We aim to prevent post-surgical adhesions using biodegradable and thermosensitive poly(ethylene glycol)-poly(ε-caprolactone)-poly(ethylene glycol) (PEG-PCL-PEG, PECE) hydrogel. In this work, we investigated the effect of PECE hydrogel on preventing post-surgical abdominal adhesions in mouse ...