Abstract Background The purpose of this study is to evaluate the influence anti-vascular endothelial growth factor (VEGF) in appearance or progression epiretinal membranes (ERMs) age-related macular degeneration (ARMD) and investigate confounding factors causing ERMs. Methods Seventy-six eyes that were treated for more than 36 months from first anti-VEGF injection assessed. Binary logistic regr...

PURPOSE To evaluate the safety and efficacy of a preoperative intravitreous injection of microplasmin in patients scheduled for vitreous surgery. DESIGN Phase 2, multicenter, placebo-controlled, double-masked, parallel-group, dose-ranging clinical trial. PARTICIPANTS One hundred twenty-five patients scheduled for pars plana vitrectomy (PPV), primarily for treatment of either vitreomacular t...

Vitreous floaters are common. Most every ophthalmologist treating adults sees new and existing patients with a chief complaint of floaters in the office on a daily basis. Yet, treatment options for bothersome floaters have traditionally been quite limited. Robert Machemer introduced pars plana vitrectomy (PPV) in the early 1970s, and with the progressively decreasing gauge size, the idea of PPV...

BACKGROUND The high incidence of retinal detachment and its poor surgical prognosis in patients with Stickler syndrome are well known. However, the vitreoretinal relation to retinal detachment in this syndrome is uncertain. METHODS Vitreoretinal examination with a binocular indirect ophthalmoscope and a Goldmann three mirror contact lens was performed on identical twin boys with Stickler synd...

Yoga has recently been touted as a means to improve physical and mental well-being. However, no form of exercise is without its risks. A 32-year-old Chinese female with moderate myopia complained of right eye sudden onset of floaters and mild blurring of vision after the head-down posture. The visual acuity was 6/12 in the right eye and 6/9 in the left eye. A right eye fundus examination showed...