1. The influence of ADH and the state of potassium balance on the renin-angiotensin system was studied in rats with hereditary diabetes insipidus (DI rats). 2. Plasma renin concentration in DI rats was higher than in control Long-Evans rats. 3. Spontaneous reversal of the hypokalaemia normally found in DI rats did not reduce plasma renin concentration (p.r.c.), suggesting that potassium deficie...

Norepinephrine metabolism, arterial blood pressure, and electrolytes were studied in rats maintained on either potassium-deficient or control diets. After 3 weeks on the test diets, the arterial blood pressure was significantly lower and the ratio of [Na] to ,[K] in cardiac tissue was significantly higher in potassiumdeficient rats as compared to controls. Ten minutes after intravenous injectio...

The relationship between the endolymphatic potential (EP) and the sodium and potassium concentration gradients between endolymph and interstitial fluid was studied both by measuring the EP at varying concentrations of sodium and potassium in endolymph and by measuring the effect of a depressed EP on the concentrations of these cations. Ethacrynic acid was used in dogs to change the concentratio...

Renal ammonium excretion is increased by potassium depletion and reduced by potassium loading. To determine whether changes in potassium concentration would alter ammonia transport in the medullary thick ascending limb (MAL), tubules from rats were perfused in vitro and effects of changes in K concentration within the physiological range (4-24 mM) were evaluated. Increasing K concentration from...

One hundred and six patients with acute myocardial infarction admitted to hospital within four hours after the onset of symptoms were randomised to treatment with intravenous timolol (54 patients) or placebo (52 patients). Serum potassium concentrations were estimated at frequent intervals during the first 24 hours of admission. Patients in both treatment groups, who did not receive subsequent ...

Microelectrode techniques were used to study isolated canine Purkinje fibers perfused alternately with Tyrode's solution and extracorporeally circulated arterial blood from heparinized donor dogs. Action potential amplitude and resting membrane potential were similar in both perfusates and varied with the potassium concentration of the perfusate. Action potential duration also varied with the p...

abstract this study was conducted to investigate, under incubation conditions (fc moisture and temperature of 30o c), the effect of the potassium concentration and the cultivation background on the k- fixation in khuzestan’s sugarcane under-cultivation soils. for this reason, 70 complex soil samples in 35 pairs each coupled out of two different depths (0-30 and 30-60 cm), chosen from the under-...

This study was performed to investigate the action of potassium channel openers on the mechanical activity of detrusor muscle isolated from rats. Detrusor muscle strips, 15 mm in length, were myographied isometrically in an isolated organ bath. P 1060, RP 49356 and BRL 38277, potassium channel activators, reduced the basal tone and diminished the phasic activity of detrusor concentration-depend...