Fifteen years have elapsed since the first human infections with H5N1 highly pathogenic avian influenza (HPAI) virus were detected in Hong Kong SAR, China [1, 2]. Many of these human infections were fatal and represented the first documented outbreak of severe disease due to HPAI viruses. The hallmark of these H5N1 viruses is their hemagglutinin genes inherited from A/goose/Guangdong/1996, a vi...

Geospatial information can act as a thread that can be used to integrate information from heterogeneous sources. It does so by exploiting common location information components that often exist across different domains. As such it has the potential to be a valuable resource in the implementation of the Semantic Web. This paper examines the challenges of adding a geospatial component to the Web,...

In colorectal cancer (CRC), the treatment guidelines differ for Union International Contrè Cancer (UICC) stage II and III colon cancer patients. In patients with stage II colon cancer without risk factors such as T4 tumor, tumor perforation, emergency surgical procedure, or less than 12 removed lymph nodes, the low risk of recurrence is justifying no role of adjuvant chemotherapy. It would be c...

We present a concise outlook of particle physics after the first LHC results at 7-8 TeV. The discovery of the Higgs boson at 126 GeV will remain as one of the major physics discoveries of our time. But also the surprising absence of any signals of new physics, if confirmed in the continuation of the LHC experiments, is going to drastically change our vision of the field. At present the indicati...

The separation of sister chromatids at the metaphase-to-anaphase transition is triggered by a protease called separase that is activated by the destruction of an inhibitory chaperone (securin). This process is mediated by a ubiquitin protein ligase called the anaphase-promoting complex or cyclosome (APC/C), along with a protein called Cdc20. It is vital that separase not be activated before eve...