Following up on our previous study, we conducted a genome-wide analysis of admixture for two Uyghur population samples (HGDP-UG and PanAsia-UG), collected from the northern and southern regions of Xinjiang in China, respectively. Both HGDP-UG and PanAsia-UG showed a substantial admixture of East-Asian (EAS) and European (EUR) ancestries, with an empirical estimation of ancestry contribution of ...

T he prevalence of type 2 diabetes is higher in populations of Native American ancestry, and in Hispanic American populations formed by admixture between Europeans and Native Americans, than in populations of European ancestry. One approach to distinguishing between environmental and genetic explanations for this difference is to study the relationship of type 2 diabetes risk to individual admi...

By comparing the sex-specifically inheritedX chromosome to the autosomes in ancient genetic samples,we (1) studied sex-specific admixture for two prehistoric migrations. For each migration we used several admixture estimation procedures—including ADMIXTURE model-based clustering (2)—to compare X-chromosomal and autosomal ancestry in contemporaneous Central Europeans and we interpreted greater a...

T he prevalence of type 2 diabetes is higher in populations of Native American ancestry, and in Hispanic American populations formed by admixture between Europeans and Native Americans, than in populations of European ancestry. One approach to distinguishing between environmental and genetic explanations for this difference is to study the relationship of type 2 diabetes risk to individual admi...

A method for simultaneously estimating the admixture proportions of a hybrid population and Wright's fixation index, FST, for that hybrid is presented. It is shown that the variance of admixture estimates can be partitioned into two components: (1) due to sample size, and (2) due to evolutionary variance (i.e., genetic drift). A chi-square test used to detect heterogeneity of admixture estimate...

Long-range migrations and the resulting admixtures between populations have been important forces shaping human genetic diversity. Most existing methods for detecting and reconstructing historical admixture events are based on allele frequency divergences or patterns of ancestry segments in chromosomes of admixed individuals. An emerging new approach harnesses the exponential decay of admixture...

This paper presents an experimental study on the nature of permeation properties and pore structure of concrete surface layers containing fly ash. Concretes containing different dosages of fly ash as a replacement for cement (15% and 30% by weight of total cement materials, respectively) were investigated. Concrete without any fly ash added was also employed as the reference specimen. Laborator...

Genetic admixture between wild and introduced populations is a rising concern for the management of endangered species. Here, we use a dual approach based on molecular analyses of samples collected before and after hatchery fish introduction in combination with a simulation study to obtain insight into the mechanisms of admixture in wild populations. Using 17 microsatellites, we genotyped pre- ...

Genetic admixture can provide material for populations to adapt to local environments, and this process has played a crucial role in the domestication of plants and animals. The model yeast, Saccharomyces cerevisiae, has been domesticated multiple times for the production of wine, sake, beer, and bread, but the high rate of admixture between yeast lineages has so far been treated as a complicat...

Estimation of admixture fractions has become one of the most commonly used computational tools in population genomics. However, there is remarkably little population genetic theory on their statistical properties. We develop theoretical results that can accurately predict means and variances of admixture proportions within a population using models with recombination and genetic drift. Based on...