Running title Early stage detection of malignant vocal fold lesions Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Abstract About two thirds of laryngeal cancers originate at the vocal cords. Early stage detection of malignant vocal fold al...

Cutaneous squamous cell carcinoma (cSCC) is a malignancy of epidermal keratinocytes that is responsible for approximately 20% of skin cancer-related death yearly. We have previously compared the microRNA (miRNA) expression profile of cSCC to healthy skin and found the dysregulation of miRNAs in human cSCC. In this study we show that miR-31 is overexpressed in cSCC (n = 68) compared to healthy s...

BACKGROUND AND AIMS Several diagnostic methods are being employed to detect benign and malignant lesions, one of which is silver nitrate staining for organizer regions. The number of nucleolar organizing regions (NORs) can be used to show the degree of cell activity or metabolism in pathologic lesions. This study was designed to evaluate NORs as determi-nants of precancerous and squamous cell c...

The geriatric population is continuously growing, which leads to more aged patients being admitted to dermatology clinics. The aim of this study is to determine the dermatological complaints of the elderly attending a dermatology outpatient clinic. All of the patients aged 65 years and older admitted to our dermatology outpatient clinic over a 1-year period were included. Patients were divided ...

PURPOSE The objective of this study was to evaluate the diagnostic concordance characteristics of oral cavity lesions by comparing the clinical diagnosis of the lesions with the histopathologic diagnosis. MATERIAL AND METHOD A retrospective analysis was conducted on the patients, who were admitted with oral cavity pathology and underwent biopsy procedure between 2007 and 2011. The oral cavity...

Purpose: Qat chewing, smoking, smokeless tobacco (locally known as shammah) and waterpipe smoking (locally known as madaah) are common habits in Yemen. The aim of this study was to investigate the prevalence of oral cancerous and precancerous lesions, and to investigate the prevalence of oral risk habits among Yemeni adults attending outpatient dental clinics, Sana‘a University. Materials and m...

background: cutaneous leishmaniasis is an annoying and disfiguring disease affecting around 1,500,000 individuals globally. there are endemic pockets of this disease in taif region. in some patients, lesion often weeps and leads to scar formation. the study was conducted to see the efficacy of fluconazole and itraconazole in the patients of cutaneous leishmaniasis and the effect of these drugs ...

The Swedish Family-Cancer Database was used to analyze relationships between parents and offspring with in situ cancers and between in situ cancers in one generation and invasive cancer in the other generation. A total of 130,000 in situ cancers and close to 400,000 invasive cancers were included from 1959 to 1994. The data on family relationships and cancers came from registered sources and sh...