نتایج جستجو برای: predominant mutations

تعداد نتایج: 215817  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علوم بهزیستی و توانبخشی 1388

qeeg به مفهوم ساده عبارتست از آنالیز کمی (quantitative) امواج یک نوار مغزی برای پی بردن به مختصات کمی موج های موجود در آن از جمله توزیع کمی امواج در محل های مختلف جمجمه یا قدرت هر کدام از امواج از نظر دامنه. در این مطالعه به منظور درک بهتر اختلال اسکیزوافکتیو ، تعداد 40 بیمار بطور تصادفی و بر اساس معیارهای ورود و خروج از مطالعه انتخاب شدند و نوار مغزی آنها که به شیوه کمی مورد آنالیز قرار گرفت...

Journal: :The Journal of clinical endocrinology and metabolism 2009
Marco Volante Ida Rapa Manoj Gandhi Gianni Bussolati Daniela Giachino Mauro Papotti Yuri E Nikiforov

CONTEXT Poorly differentiated carcinomas represent an aggressive group of thyroid tumors with controversial classification placement and poorly understood pathogenesis. Molecular data in this group of tumors are extremely heterogeneous, possibly reflecting different inclusion criteria. Recently homogeneous diagnostic criteria have been proposed by our group (Turin proposal) that need to be comp...

2014
Wensheng Zhang Andrea Edwards Erik Flemington Kun Zhang

Somatic mutation accumulation is a major cause of abnormal cell growth. However, some mutations in cancer cells may be deleterious to the survival and proliferation of the cancer cells, thus offering a protective effect to the patients. We investigated this hypothesis via a unique analysis of the clinical and somatic mutation datasets of ovarian carcinomas published by the Cancer Genome Atlas. ...

Journal: :hepatitis monthly 0
ileana constantinescu immunology of transplantation discipline, faculty of medicine, carol davila university of medicine and pharmacy, bucharest, romania; center for immunogenetics and virology, fundeni clinical institute, bucharest, romania; centre for immunogenetics and virology, fundeni clinical institute, bucharest, romania. tel: +40-744341984, fax: +40-213180448 andrei-antoniu dinu center for immunogenetics and virology, fundeni clinical institute, bucharest, romania voicu boscaiu “gheorghe mihoc-caius iacob” institute of statistics and applied mathematics, bucharest, romania marius niculescu colentina clinical hospital, bucharest, romania

conclusions genotype d was the main genotype detected in romanian patients with chronic hbv infection. genotype d presented both bcp and pc mutations more frequently. results we detected two hbv genotypes; a (8.1%) and d (60.5%), and a mixture of genotypes a and d (31.4%) (p < 0.001). basal core promoter (bcp) a1762t/g1764a and precore (pc) g1896a mutations were detected in these romanian patie...

Journal: :مجله دانشگاه علوم پزشکی شهید صدوقی یزد 0
محمدعلی حسینپورفیضی ma hosseinpour feizi عباسعلی حسینپورفیضی aa hosseinpour feizi ناصر پولادی n pouladi مهدی حقی m haghi پروین آذرفام p azarfam

introduction: recent molecular studies on iranian β-thalassemia genes revealed the presence of eight common mutations associated with thalassemia. although these mutations are frequent, there are other rare and unknown mutations that can create large problems in designing preventive programs. we detected and explained the common mutations in north-western iran previously and detection of the ra...

Journal: :Antimicrobial agents and chemotherapy 2000
L M Demeter R W Shafer P M Meehan J Holden-Wiltse M A Fischl W W Freimuth M F Para R C Reichman

The development of human immunodeficiency virus type 1 resistance to delavirdine (DLV) was studied in subjects receiving DLV monotherapy. Phenotypic resistance developed in 28 of 30 subjects within 8 weeks. K103N and Y181C, which confer nonnucleoside reverse transcriptase inhibitor (NNRTI) cross-resistance, were the predominant reverse transcriptase mutations. P236L, which confers DLV resistanc...

2010
Laura E. Cox Laura Ferraiuolo Emily F. Goodall Paul R. Heath Adrian Higginbottom Heather Mortiboys Hannah C. Hollinger Judith A. Hartley Alice Brockington Christine E. Burness Karen E. Morrison Stephen B. Wharton Andrew J. Grierson Paul G. Ince Janine Kirby Pamela J. Shaw

BACKGROUND Amyotrophic lateral sclerosis (ALS), a common late-onset neurodegenerative disease, is associated with fronto-temporal dementia (FTD) in 3-10% of patients. A mutation in CHMP2B was recently identified in a Danish pedigree with autosomal dominant FTD. Subsequently, two unrelated patients with familial ALS, one of whom also showed features of FTD, were shown to carry missense mutations...

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