نتایج جستجو برای: pregabalin
تعداد نتایج: 1977 فیلتر نتایج به سال:
BACKGROUND Clinical trials have not yet compared the efficacy of capsaicin 8% patch with current standard therapy in peripheral neuropathic pain (PNP). OBJECTIVES Head-to-head efficacy and safety trial comparing the capsaicin patch with pregabalin in PNP. METHODS Open-label, randomized, multicentre, non-inferiority trial. Patients with PNP, aged 18-80 years, were randomly assigned to either...
BACKGROUND Post-operative pain and the administration of opioids to relieve it, is considered to be one of the important issues in surgery wards. This issue is even more significant in obese patients, because of the side effects of opioids. Pregabalin is an analog of gamma aminobutyric acid (GABA) which can be effective in dealing with post-operative pain. OBJECTIVES This study will consider ...
*****Department of Pediatrics, Midnapore Medical College, Midnapore, West Bengal, India Objective: Post herpetic neuralgia is a most common complication of herpes zoster which is difficult to treat. Significant beneficial effects found when treated with antiviral, tricyclic antidepressant, anticonvulsive like gabapentine and pregabalin, opioid and non opioid analgesic etc. Primary prevention ca...
BACKGROUND Fibromyalgia (FM) is a common pain condition characterized by widespread musculoskeletal pain and tenderness. Pregabalin is an approved treatment for adults in the United States, but there are no approved treatments for adolescents with FM. METHODS This was a 15-week, randomized, double-blind, placebo-controlled study and 6-month open-label safety trial of flexible-dose pregabalin ...
Between January 2008 and August 2010, qualitative Google searches of 203 websites have been carried out in 8 European languages (English, German, Spanish, Italian, Dutch, Norwegian, Finnish, Swedish) using key words such as ‘legal highs’, ‘research chemicals’, ‘online pharmacy’, ‘Lyrica’, ‘pregabalin’, and ‘online pharmacies’. Out of these, 108 websites were monitored on a regular basis, i.e. d...
Pregabalin is an antiepileptic and analgesic drug, commercialized under the name of Lyrica, and generally used to treat neuropathic pain. The determination of pregabalin was performed by using spiked hair samples extracted in methanol and analyzed by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry. The validation of a quantification method of pregabalin in hai...
Pregabalin is one of the first-line treatments approved for management neuropathic pain (NeP). While many patients benefit from treatment with pregabalin, they are often treated suboptimal doses, possibly due to unfamiliarity around prescribing drug and/or side effects that can occur up-titration. This narrative review discusses key aspects initiating, titrating, and managing prescribed pregaba...
Pregabalin is a new generation antiepileptic that exerts its effect by decreasing the release of such neurotransmitters as glutamate, noradrenaline, and substance P. Pregabalin can be prescribed in Turkey at 150-600 mg to treat neuropathic pain, generalized anxiety disorder, fibromyalgia, and as concomitant therapy in adult patients with partial epilepsy. Experimental studies have shown that pr...
The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common cause of euvolemic hyponatremia, and many medications have been associated with SIADH. Pregabalin is a drug used for the treatment of neuropathic pain, though common adverse effects include central nervous system disturbance, peripheral edema, and weight gain. However, hyponatremia caused by pregabalin has b...
In human, digestive disorders are often associated with visceral pain. In these pathologies, visceral pain threshold is decreased indicating a visceral hypersensitivity. Pregabalin [CI-1008; S-(+)-3-isobutylgaba] presents antihyperalgesic actions in inflammatory somatic pain models. This study was designed to evaluate 1) the effect of injection of TNBS into the colon on visceral pain threshold,...
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