BACKGROUND Preterm birth is a leading cause of perinatal morbidity and mortality worldwide, resulting in a pressing need to identify risk factors leading to effective interventions. Limited evidence suggests potential relationships between maternal sleep or vital exhaustion and preterm birth, yet the literature is generally inconclusive. METHODS We examined the relationship between maternal s...

In order to assess racial differences in rates of idiopathic preterm labour, preterm premature rupture of membranes, and medically indicated preterm delivery, the authors analysed data on 388 preterm (< 37 completed weeks of gestation) births (7.9% of all births) occurring between 1 September 1988 and 31 August 1989, in three central North Carolina counties. The crude relative risk (RR) of pret...

Objectives: Evaluation of the premature ruptured membranes incidence in a neonatology service, identification of microbial agents involved in producing infections with intrapartum onset and analysis of clinical and evolutive parameters involved in these cases. Material and method: Anamnestic, clinical and paraclinical data research, on all newborns resulted from premature ruptured membranes lab...

BACKGROUND: Premature Rupture of Membranes (PROM) is significantly linked to the infections-related maternal deaths. In inflammatory process, influencing stressor will stimulate activation Nuclear Factor Kappa B (NF-κB) and Receptor Advanced Gyclation End product (RAGE). Yet up date, expression NF-κB RAGE in pregnant women with PROM are still rarely studied. Therefore, this study aimed observe ...

OBJECTIVE To compare inflammatory mediators in the cord blood of premature newborn infants with premature rupture of membranes (PROM) and intact membranes. METHODS Eighty-nine premature neonates with gestational age of 27-34 weeks that delivered in Ghaem Hospital in Mashhad, Iran from June 2005 to March 2006 were enrolled in a prospective observational study, and their umbilical cord plasma w...

Premature Rupture of Membranes (PROM) is defined as rupture of membranes prior to onset of labor. It can occur at any gestational week. PROM greater than 24 hours is referred as prolonged PROM and carries risk of ascending infection (1). PROM occurs in 8%-10% of all term pregnancies and in 2%-4% of all preterm singleton pregnancies (1,2). The most important maternal risk is intrauterine infecti...

This study aims to explore potential clinical relevance of sHLA-G to premature rupture of membrane. 75 samples of pregnancy were enrolled, including patients with preterm premature rupture of membranes (PPROM), patients with term premature rupture of membranes (TPROM) and normal pregnancy women. Level of sHLA-G in multiple sites were examined with ELISA. Lymphocytes were isolated from periphera...