BACKGROUND Serotonin influences the development of the hypothalamic-pituitary-adrenal (HPA) system; therefore prenatal exposure to selective serotonin reuptake inhibitor antidepressants (SSRIs) may alter HPA axis development and function. To address this, prenatal exposure to SSRIs and maternal mood were examined in relation to neonatal and infant levels of cortisol and its binding protein, cor...

Background To investigate the effects of negative emotions and life events on women's missed miscarriage. Methods Overall, 214 women diagnosed with a missed miscarriage by prenatal examination from 2016-2017 in Xiamen Maternal and Child Health Care Hospital, Xiamen, China were selected as the observation group compared to 214 women as control group. The general data of the patients were inves...

OBJECTIVE To investigate the association between postpartum depression and the occurrence of exclusive breastfeeding. METHOD This is a cross-sectional study conducted in the states of the Northeast region, during the vaccination campaign in 2010. The sample consisted of 2583 mother-child pairs, with children aged from 15 days to 3 months. The Edinburgh Postnatal Depression Scale was used to s...

The composition of human milk is subject to considerable variation, but the effects maternal stress are largely unknown. We studied differences in metabolome between Finnish mothers (n = 120, secretors) with symptoms prenatal psychological distress and cortisol concentrations. Human samples acquired at 2.5 months postpartum were analyzed using targeted 1H NMR metabolomics. Self-reported scores ...

BACKGROUND Twin pregnancies are at increased physiological and psychosocial risks. OBJECTIVE To investigate the prevalence of major depression in twin pregnancies and correlate with stress and social support. METHOD The study included 51 pregnant women under specialized prenatal care who were evaluated by a Portuguese version of the semi-structured questionnaire Primary Care Evaluation of M...

Variation in the influence of prenatal androgens is thought to be reflected in an individual s finger length ratio (2D:4D). Many recent studies have examined the relationship between adult finger length ratio and traits thought to be affected by prenatal androgens. For example, Martin, Manning, and Dowrick (1999) have suggested that increased risk of clinical depression is a cost of high organi...

OBJECTIVE To examine whether depressive symptoms are a risk factor for a subsequent pregnancy in adolescent mothers. DESIGN Secondary analysis from a longitudinal risk-reduction intervention. SETTING Five community-based prenatal sites in Baltimore, Maryland. PARTICIPANTS Two hundred sixty-nine consenting teens, predominantly African American and with low income, who received prenatal car...

OBJECTIVE The purpose of this article was to systematically compare the developmental trajectory of neurobehavior over the first postnatal month for infants with prenatal exposure to pharmacologically untreated maternal depression, selective serotonin reuptake inhibitors or serotonin and norepinephrine reuptake inhibitors (collectively: SSRIs), SSRIs with concomitant benzodiazepines (SSRI plus ...