2. Thiomersal and timerfonate are organomercuric compounds used as preservatives in vaccines, antigens and immunoglobulins intended for use in humans and animals. At present these substances seem to best fulfil the requirements for efficacious preservatives used in inactivated vaccines because they do not react with antigen and are effective at very low concentrations. According to the recent s...

The toxicity of preservatives on conjunctival epithelium has been widely described in glaucomatous patients topically treated, suggesting both an indirect effect on the lacrimal film and a direct toxic action on epithelial cells (1). Previous studies indicate that long-term administration of preservative-containing eyedrops can lead to chronic conjunctival inflammation, ocular surface impairmen...

Sections of the Howe truss railway bridge at Waikino that had been treated with preservatives were inspected after approximately 12 months. There were minor colour changes, particularly where CD50 and Busan 30L had been applied to the surface. CD50 was the only surface treatment which was still water-repellent. Of the preservatives which had been inserted into holes bored in the stringers, the ...

Thirteen nonacidic waterborne preservatives were in­ vestigated for their compatibilitywith phenol-formaldehyde adhesive on aspen veneer treated with the preservatives to retentions of 0.2, 0.4, and 0.6 pcf. Of these preserva­ tives, didecyl dimethyl ammonium chloride (DDAC),DDAC with copper, DDAC with carbamate (DDACCA),sodium fluoride,and ammonium hydrogen difluoridedid not inter­ fere with a...

Pharmaceutical preparations usually contain preservatives and sweeteners. When parabens are used as preservatives and a polyol as a sweetener, a transesterification reaction may happen, yielding the transester polyol-paraben. The products formed in the transesterification reaction of methylparaben and sorbitol were analyzed by micellar electrokinetic chromatography and by HPLC. Up to six positi...

Microbial safety of food products is often accomplished by the formulation of food-grade preservatives into the product. Because of the growing consumer demand for natural substances (including preservatives) in the composition of consumed foods, there is also a growing interest in the natural antimicrobial nisin, which has generally recognized as safe (GRAS) status for certain applications. Du...

An adequate service life of wooden structures in the sea is ensured only: If wood is treated with biocide wood preservatives with high retention level or; If some tropical hardwoods, with known natural resistance, are used. However, the poor public image of use the tropical hardwoods, as contribution to deforestation at one hand and legal requirements to restrict the use of biocide preservative...

Topical glaucoma therapy is a long termed, usually lifelong. Antiglaucomatous drugs have toxic effects on ocular surface, due to preservative toxicitiy or the drug itself. Adding a lubricant eyedrops to antiglaucomatous therapy, especially if considering the preservative used, can have protective effect. The purpose of this study was to evaluate the stabilty of precorneal tear film in glaucoma ...