OBJECTIVE The purpose of this study was to explore the association between tuberculin reaction size in contacts with positive tuberculin skin test results and a variety of contact and index patient variables. PATIENTS AND METHODS We reviewed the contact investigation records for tuberculosis patients identified by the Tuberculosis Prevention and Control Center of Lleida, Spain, over a period ...

recent studies have proposed that a decline in bacterial infections such as tuberculosis is a factor underlying the rising prevalence and severity of atopic disorder in developed countries. there are conflicting ideas about the inverse relationship between bcg (bacillus calmette-guerin) vaccination and asthma. stronger response to tuberculin test as an indicator of more potent th1 response is s...

BACKGROUND The prevalence of asymptomatic tuberculosis (TB) in recently diagnosed HIV-1-infected persons attending pre-antiretroviral therapy (ART) clinics is not well described. In addition, it is unclear if the detection of Mycobacterium tuberculosis in these patients clearly represents an early asymptomatic phase leading to progressive disease or transient excretion of bacilli. OBJECTIVE T...

background there is a high risk of tuberculosis (tb) infection among injecting drug users (idus). objectives this study aimed to determine the frequency of latent and active tb infection among idus. materials and methods in a cross-sectional study between 2008 and 2009, idus referred to the methadone maintenance treatment (mmt) centers in hamedan-iran, undergone tuberculin skin test (ppd; purif...

A large proportion of tuber culin tests in tropical countries yield weak or doubtful reactions. Since leprosy is common in many of the countries where this phenomenon has been observed, it has been suggested that some of these anomalous r eactions may be due to nonspecific sensitization to mycobacterial antigens common to both the leprosy and the tubercle bacilli, The positive tuberculin hemagg...

This study was aimed at investigating the immunologic relationship between cytokine production pattern and tuberculin negativity in patients with active Mycobacterium tuberculosis infection. After classifying patients by the extent of pulmonary involvement and the size of the tuberculin reaction, we evaluated the rate of cytokine positivity in peripheral blood to determine whether there is a ch...

The collapse of North Korea's public health system has increased the development of tuberculosis (TB) in its populace. This study investigated the prevalence of active and latent TB infection (LTBI) in such people who have settled in the Republic of Korea since 1999. From 1999 to August 2006, 7,722 dislocated North Koreans entered the Republic of Korea and all were screened immediately for acti...

BACKGROUND Cutaneous sensitivity to the tuberculin antigen is thought to indicate latent tuberculosis infection (LTBI). Some guidelines suggest treating end-stage renal disease (ESRD) patients for LTBI on the basis of tuberculin positivity. The prevalence of tuberculin sensitivity and cutaneous anergy in Indian patients with ESRD and the utility of the tuberculin test for predicting post-transp...

The aim was to study the tuberculin skin test in relation to immunological in vitro reactions in bacille Calmette-Guerin (BCG)-vaccinated healthcare workers. The present study was performed in Sweden, a country with a low incidence of tuberculosis, a high BCG vaccination efficacy and high tuberculin conversion rates. BCG-vaccinated healthcare workers (n=381) were tuberculin skin tested. From th...