Androgen insensitivity syndrome is a rare disease, manifested as normal female external phenotype to infertile male with 46 XY karyotype due to different level of resistance of androgen receptor. Androgen insensitivy syndrome is classified as complete, partial and mild androgen insensitivity. Partial androgen insensitivity syndrome is further subclassified according to morphogenesis as predomin...

Primary amenorrhoea is a symptom with an extensive list of underlying causes, the majority of which are rare. By definition it should present in adolescence, although some conditions diagnosed in childhood may anticipate the failure of onset of menstruation. Many causes of secon­ dary amenorrhoea can also present with primary amenorrhoea if they arise sufficiently early. This review addresses s...

A 29-year-old woman presented with secondary amenorrhea, primary infertility, and virilization, which had developed over the past 2 years was suspected to have a virilizing tumor at her left ovary. Her serum testosterone level was markedly elevated (380 ng/dL). Left salpingoophorectomy was performed, and histopathological examination revealed a thecoma of the left ovary. The postoperative serum...

BACKGROUND The aim of the present study was to investigate the chromosomal abnormalities and to identify the most prevalent or frequent type of chromosomal abnormalities in cases of amenorrhea from the southern region of India. METHODS A total of 637 cases with amenorrhea were analyzed using G- banding, C-banding, Silver staining, and fluorescence in situ hybridization was done wherever neces...

Urethral coitus is a rare condition seen especially in cases with vaginal agenesis or hymen imperforatus. A female patient with sexual dysfunction and primary amenorrhea diagnosed with urethral coitus is presented in this report. These cases present recurrent urinary tract infections, dysuria, and dyspareunia besides primary amenorrhea. There was no megalourethra or vaginal introitus in our cas...

PURPOSE OF REVIEW We present an update on amenorrhea in adolescent girls and young women. Amenorrhea may herald the onset of estrogen deficiency, which can adversely affect peak bone mass and ultimate risk of osteoporosis. RECENT FINDINGS Adolescence is a critical period for bone accretion. Important modifiable factors that optimize bone accretion during this time are calcium intake, vitamin ...

Breastfeeding provides a natural source of nutrients for the infant and determines a period of Lactational Amenorrhea (LA) as a normal postpartum physiological phenomenon. Universally, it is now recognized that breastfeeding suppresses ovarian cyclicity and provides LA condition accompanied by a period of postpartum infertility. The duration of the LA period varies among different women and pop...

In a survey of 75 dancers (mean age, 24.3 years) in four professional ballet companies, we found that the prevalence of scoliosis was 24 percent and that it rose with increases in age at menarche. Fifteen of 18 dancers (83 percent) with scoliosis had had a delayed menarche (14 years or older), as compared with 31 of 57 dancers (54 percent) without scoliosis (P less than 0.04). The dancers with ...