Protein-losing enteropathy (PLE) is a rare complication of a variety of intestinal disorders characterized by an excessive loss of proteins into the gastrointestinal tract due to impaired integrity of the mucosa. The clinical presentation of patients with PLE is highly variable, depending upon the underlying cause, but mainly consists of edema due to hypoproteinemia. While considering PLE, othe...

The syndrome of protracted diarrhea (PD) includes several diseases with diverse etiologies. This study was conducted to characterize the spectrum of causes, clinical manifestations, and the outcomes of PD. A retrospective analysis of the clinical and pathological findings was performed on 25 patients with diarrhea starting within the first 2 yr of life and a requirement of parenteral nutrition ...

Intestinal polypoid lymphangiectasia is an uncommon disorder involving improperly formed enteric lymphatic system. It characterized by vessel dilatation with impaired drainage or obstruction of the lymph from intestine. In this report, we present a case 73-year-old male patient chronic intermittent left lower quadrant abdominal pain for one year who was found to have sigmoid colon polyp on colo...

Intestinal lymphangiectasia is a well-recognized complication of the Fontan procedure, occurring in up to 24% of patients. Because of the loss of chylous fluid into the gut lumen, protein-losing enteropathy results as well as lymphopenia and hypogammaglobulinaemia. In some cases, dilated lymphatics in the intestinal serosa or mesentery also rupture, causing chylous ascites. Standard medical and...

The occurrence of exudative enteropathy in children with the nephrotic syndrome was first reported by Nussle et al. in 1961, but no intestinal pathology has previously been described in nephrotic children, whether with or without protein-losing enteropathy. The finding in small bowel biopsy specimens of intestinal lymphangiectasia, in 4 of 7 cases of nephrotic syndrome, suggests that this assoc...