controversial immunomodulatory properties of bee venom (bv) have provided an appropriate field for more investigation. the aim of present research was to verify the effects of honeybee venom on matrix metalloproteinase activity and interferon production as well as cell proliferation in monocyte and fibroblast cell lines. the monocyte and fibroblast cell lines (k562, ht-1080, wehi-164) were used...

Objective We have previously shown that Rose Bengal (RB) alone, not as a photosensitiser, could induce apoptotic- and non-apoptotic cell death in different melanoma cell lines. To clarify RB-induced toxicity mechanisms, role of caspases and reactive oxygen specious (ROS) were studied in melanoma cells. Material and Methods Human melanoma cell lines, Me 4405 and Sk-Mel-28 were cultured in DM...

Assembly lines are flow-oriented production systems that are of great importance in the industrial production of standard, high-volume products and even more recently, they have become commonplace in producing low-volume custom products. The main goal of designers of these lines is to increase the efficiency of the system and therefore, the assembly line balancing to achieve an optimal system i...

  An optimal desirability function method is proposed to optimize multiple responses in multiple production scenarios, simultaneously. In dynamic environments, changes in production requirements in each condition create different production scenarios. Therefore, in multiple production scenarios like producing in several production lines with different technologies in a factory, various fitted r...