background: the natural history and etiology of malignant mesothelioma (mm) is already thoroughly described in the literature, but there is still debate on prognostic factors, and details of asbestos exposure and possible context with clinical and demographic data, have not been investigated comprehensively. objectives: description of patients with mm, focusing on exposure, occupation, survival...

Oral drugs stimulating endogenous insulin production (insulin secretagogues) may have detrimental effects on breast cancer outcomes. The data presented shows the relationship between pre-existing insulin secretagogues use, adipokine profiles at the time of breast cancer (BC) diagnosis and subsequent cancer outcomes in women diagnosed with BC and type 2 diabetes mellitus (T2DM). The Pearson corr...

background: thioredoxin reductase 1 (txnrd1) and thioredoxin interacting protein (txnip) also known as thioredoxin binding protein 2 or vitamin d3-upregulated protein 1 are key players in oxidative stress control. thioredoxin (trx) is one of the major components of the thiol reducing system and plays multiple roles in cellular processes. computational analyses of txnrd1, txnip and trx expressio...

Background & Objectives: Colon cancer is currently of high incidence and mortality rate. Identifying the factors influencing its prognosis can be very beneficial to its clinical treatment. Recent studies have shown that lymph nodes ratio can be considered as an important prognostic factor. The aim of the present study is to investigate the effect of this factor on the prognosis of the ...

the aim of this study was investigating the characteristic and outcome of self-immolation cases admitted to the burn centre of birjand, iran over an eight year period. this study is a retrospective review of case notes for patients with self-immolation and admitted to our referral burn centre in the last 8 years (january 2003-january 2011). a performa was designed to collect the data such as: d...

background: acute methanol poisoning is one of the most important chemical poisoning due to drinking of illegal and handmade alcoholic beverages in iran. the aim of this study was to evaluate clinical and biochemical parameters as prognostic factor in acute methanol poisoning. methods: a retrospective study was performed on acute methanol poisoning cases admitted to the loghman hakim hospital p...

today, the treatment of patellar luxations using current techniques has become a very common procedureas part of the surgical treatment. nevertheless, there are some doubts about such procedures in restraining the patella in lower grade cases. the purpose of the present retrospective clinical study was to determine theefficacy of the soft tissue and bone reconstructive procedures used for vario...

background: acute myeloid leukemia (aml) is a malignant disorder involving blood cells, characterized by obstructed or distorted differentiation of hematopoietic stem cells. in cytogenetically normal aml (cn aml), molecular abnormalities in npm, flt3, cebpa, and baalc genes are observed. initially, high baalc (brain and acute leukemia cytoplasmic gene) expression was introduced in a study on am...

Integrated Systems Health Management includes fault detection, fault diagnosis (or fault isolation), and fault prognosis. We define prognosis to be detecting the precursors of a failure, and predicting how much time remains before a likely failure. Algorithms that use the data-driven approach to prognosis learn models directly from the data, rather than using a hand-built model based on human e...