Idelalisib es un inhibidor selectivo de la fosfatidilinositol 3-quinasa p110δ, cuya señalización es hiperactiva en muchas leucemias y linfomas de células B1,2. Se han documentado infecciones graves y mortales con idelalisib asociadas a Pneumocystis jirovecii (NPJ) y Citomegalovirus (CMV). La Agencia Española de Medicamentos y Productos Sanitarios (AEMPS) en base a las conclusiones del Comité pa...

We raise fundamental questions about macroeconomics relevant to escaping the financial and economic crisis and shifting to a sustainable economy. First, the feasibility of decoupling environmental pressure from aggregate income is considered. Decoupling as a single environmental strategy is found to be very risky. Next, three main arguments for economic growth are examined: growth as progress, ...

Introduction Used in the private or public USP Performance test, dissolution testing plays an important role in both product development and quality assurance for nonsolution oral dosage forms. The dissolution procedure itself,as described in USP General Chapter Dissolution <711>, is sensitive and specific but requires special care in execution. Results of a recent USP collaborative study of ne...

The Index of Sustainable Economic Welfare (ISEW) was first calculated for the United States by Daly and Cobb (1989). It draws upon an earlier tradition of attempts to build a comprehensive indicator of economic welfare, beginning with Nordhaus and Tobin (1972). Since then it has been applied to a handful of other countries, including several in Western Europe as well as Australia, Chile and Tha...

In this paper we have extracted various features from the images and evaluate their performance for various steganography tools with different classifier like J48, SMO, Naive bayes’s . There are so many steganography tools and many of them are changing the original images statistically during embedding process. To calculate that changes we are extracting various features from the cover image an...