This article presents a rare case of a common disease, prostate cancer. A 57 year-old patient undergoing annual check-up for prostate cancer presents with a prostate specific antigen (PSA) level as low as 0.64 ng/ml. This patient was revealed to suffer from prostate cancer pT2c pNx pMx. This article assesses the implications of low prostate specific antigen for prostate cancer and discusses the...

A special form of prostate cancer is non-metastatic castration-resistant cancer. Patients with this have rising prostate-specific antigen and castrate testosterone levels, no radiological findings metastatic disease on computed tomography bone scan. The phase III trials demonstrated apalutamide, darolutamide or enzalutamide to be associated a significantly longer median metastasis-free survival...

introduction: prostatic specific antigen (psa) is an important tumor marker of prostatic cancer and antigenic determinant of prostatic tissue. however, recently, results of several  researches have proposed existence of psa in non- prostatic tumors, extracts . in this study, our goal was to find that if patients with non-prostatic cancers synthesize psa. materials & methods : the sample was sel...

Prostate cancer is the most commonly diagnosed and second leading cause of mortality in men Western World. In initial stages, prostate dependent on androgens for growth which basis androgen ablation therapy. The effects are mediated by Androgen Receptor (AR). Therefore, studies focus identification AR-regulated genes that also highly expressed prostate. STAMP family STAMP1/STEAP2 STAMP2/STEAP4 ...

lymph node (ln) metastasis is considered an important prognostic factor in patients with prostate cancer. the aim of this study was to determine the rate of ln metastasis among an iranian population who underwent radical prostatectomy (rp) with pelvic ln dissection (plnd). in a retrospective review of medical records, 450 rp cases were included and the data on ln metastasis were extracted from ...

Background: The total serum prostate-specific antigen has been used as a screening tool to determine prostate health and is routinely done after a clinical exam which may include a digital rectal exam. The complexed prostate-specific antigen is a portion of the total prostate-specific antigen and may be a better indicator for prostate health. The purpose of this paper is to evaluate the effect ...

PURPOSE In patients treated with radical prostatectomy who have biochemical recurrence we have previously reported that time from surgery to biochemical recurrence and postoperative prostate specific antigen doubling time are significantly related to the risk of prostate cancer death. We performed a more thorough examination of the association of time from surgery to biochemical recurrence and ...