Background: Different studies assessed the role of inflammation in malignancy of different organs. Prostatitis has been suggested as a cause of cancer and BPH. Till now, more than 100 types of human Papilloma virus (HPV) are recognized including low and high-risk groups for carcinogenesis. Among them HPV-16 and HPV-18 have shown further association with cancer. Regarding the pr...

The aim of this project was to investigate the expression and significance of S100P, CD147, and OCT4 in prostate cancer tissue at different TNM stages. We enrolled 54 patients with prostate cancer, 40 with benign prostatic hyperplasia, and 20 subjects with normal prostates. S100P, CD147, and OCT4 were detected by immunohistochemistry. The positive rate of S100P detection was 18.52% in prostate ...

Benign prostatic hyperplasia is a nonmalignant adenomatous enlargement of the periurethral prostate gland. It is a common disease in older men. In addition to man, spontaneous benign prostatic hyperplasia occurs in chimpanzee and the dog. Alternatives to these spontaneous models are induced benign prostatic hyperplasia, xenografts and in vitro models. Xenografts may be induced by cells cultured...

OBJECTIVE To explore the inhibitive effect of soybean isoflavone on the prostatic hyperplasia on the expressions of nitric oxid and nitric oxide synthase in the prostatic hyperplasia rats. METHODS Subcutaneously injected testosterone propionate were to induce prostate hyperplasia in rats. The changes of prostate wet weight, prostatic index, liver index, the changes of some biochemical indexes...

The study was conducted on 90 serum samples of people with prostate diseases (G1-include 24 for patients cancer-PC , G2- include benign prostatic hyperplasia-BPH and 22 prostatitis G3), compared 20 healthy individuals as control group. Prostate-specific antigen-PSA, human kallikrein-2-hK2, fibrinogen gamma-FGG, total anti-oxidant capacity-TAC, Vitamin D3-VD3. results showed that the activity PS...

Mutation of LKB1 is the key molecular event underlying Peutz-Jeghers syndrome, a dominantly inherited condition characterized by a predisposition to a range of malignancies, including those of the reproductive system. We report here the use of a Cre-LoxP strategy to directly address the role of Lkb1 in prostate neoplasia. Recombination of a LoxP-flanked Lkb1 allele within all four murine prosta...

Background: Benign Prostatic Hyperplasia is a common condition in the elderly population. It affects physical health status persons over 65 years and interferes with their daily activities. Study Aim: to assess knowledge care seeking behaviors among old age patients hyperplasia Sample: aged 60 above diagnosed benign prostatic hyperplasia. The total sample size was 218 elderly. Cross-sectional r...

Background: Prostate specific antigen (PSA) has been used as a screening test for the early detection of prostate cancer (PC) for many years. Although the introduction of PSA test led to a considerable increase in reported prostate cancer cases, there is still some controversy over the sensitivity and specificity of this marker in distinguishing PC patients from those with benign prostate hyper...

Objective: Exploring the clinical efficacy of transurethral plasma enucleation prostate in treatment benign prostatic hyperplasia with underactive bladder detrusor contractility. Methods: Retrospective analysis data 68 patients and muscle contractility treated by our department from July 2021 to 2022. The above all met diagnosis hyperplasia, excluding cancer urethral stricture. Urodynamics show...

androgenic alopecia as a physiologic process and benign prostatic hyperplasia (bph) as a pathologic process in the older population are androgen-dependent processes influenced by 5-alpha reductase enzyme which converts testosterone to dihydrotestosterone. this cross sectional study was done to evaluate the relationship between androgenic alopecia and bph. 150 men older than 50 years old, who pr...