background it has been found that itpase deficiency is caused by itpa gene polymorphisms. it was observed that itpa polymorphisms have impact on hematological changes, including hemoglobin (hb)-decline during treatment of chronic hepatitis c (chc) patients with pegylated-interferon (peg-ifn) plus ribavirin (rbv). conclusions in patients with chc, who were treated with peg-ifn plus rbv, hb-decli...

conclusions sch is associated with increased level of pla2-iia, which is independent of bmi. the stronger association of sch with pla2-iia than with hs-crp indicates that pla2-iia is an inducer of inflammation while hs-crp is not. results serum levels of tg, cholesterol, and ldl were higher in the sch group than the control group. however, there was no significant difference between the two gro...

background and objectives: giant cell tumor of bone (gct) is often regarded as a benign tumor, but its clinical course is unpredictable, has a high rate of recurrence, and even can metastases and transform to a malignant tumor. histological features of the tumor often could not predict its future biologic behavior, so it is just called ''giant cell tumor'' without indicating malignancy or benig...

Transpeptidase-catalyzed protein and peptide modifications have been widely utilized for generating conjugates of interest biological investigation or therapeutic applications. However, all known transpeptidases are constrained to ligating in the N-to-C orientation, limiting scope attainable products. Here, we report that an engineered asparaginyl ligase accepts diverse incoming nucleophile sub...

This study aimed to improve the quality of cryopreserved goat semen for artificial insemination by the addition of cattle seminal plasma crude protein. Semen collected from cattle and centrifuged to obtain seminal plasma. Then it was purified to obtain the crude protein. The diluent used in this study was milk-yolk. There were three groups, control group without crude protein (P0), the addition...

background: polycystic ovary syndrome (pcos) causes an increased risk of metabolic cardiovascular syndrome. also, cystatin c serum levels are associated with the risk of cardiovascular events in metabolic syndrome patients. objective: to investigate the relationship between cystatin c in pcos patients. materials and methods: 35 women with pcos were compared to 35 women with healthy matched age ...

abstract          background and objective: vitamins c and e are  the two main antioxidants involved in prevention of type 2 diabetes, by reducing oxidative stress. the aim of this study was to evaluate the effects of vitamins c and e supplementation independently, on serum levels of insulin, high sensitivity c-reactive protein (hs-crp) and resistin in people with type 2 diabetes.         metho...