protein status of 194 pregnant women and their newborn at a public and a private maternity hospital in tehran was studied. blood samples were taken from all women before delivery and from cords at delivery of the placenta. the following determinations were made: total serum protein, protein fractions, creatinine and urea. in the private group, significantly higher maternal mean values were foun...

Proteins are biological macromolecules involved in a wide range of functions, which makes them very appealing as therapeutics agents. Indeed, compared to small molecule drugs, their endogenous nature ensures biocompatibility and biodegradability, they can be used large applications present higher specificity activity. However, suffer from unfolding, enzymatic degradation, short half-life poor m...

Novel drug delivery systems for controlled-release of opioid agonists as a long time painkillers or opioid antagonists for opium, heroin, and alcohol addiction are under development or in clinical use today. In this article, the field of “new drug delivery systems” is momentarily reviewed from the viewpoint of the marketed opioid agonists/antagonists dosage forms today.

objective(s):despite of wide range applications of polymeric nanoparticles in protein delivery, there are some problems for the field of protein entrapment, initial burst and controlled release profile.   materials and methods: in this study, we investigated the influence of some changes in plga nanoparticles formulation to improve the initial and controlled release profile. selected parameters ...