The validity of the Michaelis-Menten-Briggs-Haldane approximation for single enzyme reactions has recently been improved by the formalism of the total quasi-steady-state approximation. This approach is here extended to fully competitive systems, and a criterion for its validity is provided. We show that it extends the Michaelis-Menten-Briggs-Haldane approximation for such systems for a wide ran...

In December 2003, seventeen years after the first UK research assessment exercise, Italy started up its first-ever national research evaluation, with the aim to evaluate, using the peer review method, the excellence of the national research production. The evaluation involved 20 disciplinary areas, 102 research structures, 18,500 research products and 6,661 peer reviewers (1,465 from abroad); i...

Ameisen: Die heimliche Weltmacht (Ants: Nature's Secret Power) is a nature documentary about ants. Wolfgang Thaler wrote, filmed, and directed the film, which focuses on the work of ant researcher Bert Hölldobler. The 2004 film was produced by Adi Mayer Film for Österreichischer Rundfunk (Austrian Broadcasting), a public service broadcaster headquartered in Vienna, Austria. Ants: Nature's Secre...

Consider observation data, comprised of n observation vectors with values on a set of attributes. This gives us n points in attribute space. Having data structured as a tree, implied by having our observations embedded in an ultrametric topology, offers great advantage for proximity searching. If we have preprocessed data through such an embedding, then an observation’s nearest neighbor is foun...

Nowadays modern cars integrate advanced driving assistance systems which range up to fully automated driving modes. Since fully automated driving modes have not come into everyday practice yet, operators are currently making use of assistance systems. While still being in control of the vehicle, alerts signal possible collision dangers when, for example, parking. The reason for the necessity of...

Geometric Near-neighbor Access Tree (GNAT) is a metric space indexing method based on hierarchical hyperplane partitioning of the space. While GNAT is very efficient in proximity searching, it has a bad reputation of being a memory hog. We show that this is partially based on too coarse analysis, and that the memory requirements can be lowered while at the same time improving the search efficie...

We use household survey data from the UK to study how close ‘middle-aged’ men and women in partnerships live to their own parents and their partner’s parents. We find a slight tendency for couples to live closer to the woman’s parents than the man’s. This tendency is more pronounced among couples in which neither partner has a degree and in which there is a child. In other respects, proximity t...

This paper presents a new algorithm for real-time tracking of pairs of closest points as well as their corresponding surface features between certain general types of objects (which can be non-convex) with parametric curved surfaces. The fact that the algorithm works directly on accurate parametric descriptions of curved surfaces rather than polygonal approximation of surfaces (i.e., polygonal ...

Rhodamine B (RhB) is a water-soluble fluorescent dye that is often used to determine flux and flow direction in biotechnological and environmental applications. In the current research, RhB in soluble (termed free) and virus-bound (termed nano-bound) forms was used as an efficiency indicator for three environmental processes. The degradation of free and nano-bound RhB by (i) direct UV photolysi...

Genomic instability is a major feature of neoplastic development in colorectal carcinoma and other cancers. Specific genomic instability events, such as deletions in chromosomes and other alterations in gene copy number, have potential utility as biologically relevant prognostic biomarkers. For example, genomic deletions on chromosome arm 18q are an indicator of colorectal carcinoma behavior an...