Background: Cell therapy and cell culture have received much attention in recent decades. Suitable cell growth requires growth supplements such as fetal bovine serum (FBS). FBS is component rich in nutrients, growth factors and supplementary compounds. However, FBS utilization has some limitations including mass production. Therefore, finding alternatives with the same growth promoting effects ...

conclusions prp dressing could significantly decrease the depth and surface area of dfus in a three-week period. background some of the studies confirmed the effectiveness of platelet rich plasma (prp) in the treatment of diabetic foot ulcers (dfu). however, these studies had small sample size and used different methods such as prp gel or prp injections. the results are also contraversial. obje...

background recently, the clinical use of low power lasers has increased, and it is said that wound healing is accelerated by their irradiation. the aim of this study was evaluation of the effect of platelet-rich plasma on proliferation and differentiation of human dental pulp stem cells with or without ga-al-as laser. methods: in this experimental study, human lower third molar dental pulp cell...

BACKGROUND Platelet rich plasma is known for its hemostatic, adhesive and healing properties in view of the multiple growth factors released from the platelets to the site of wound. The primary objective of this study was to use autologous platelet rich plasma (PRP) in wound beds for anchorage of skin grafts instead of conventional methods like sutures, staplers or glue. METHODS In a single ...

the clinical use of prp therapy in the practical setting of orthopaedic fields is increasing partly because of the accessibility of devices that are used in outpatient preparation and delivery. another reason is the strong advertisement of prp procedures as the ultimate treatment and novel technology for knee problems by a few orthopaedic surgeons based on claims of abundant scientific evidence...

background: osteoarthritis is a disabling musculoskeletal disease with no definite treatment. this study compared the effect of platelet-rich plasma (prp) and transcutaneous electrical nerve stimulation (tens) plus exercise in the treatment of patients with knee joint osteoarthritis.   methods : 54 eligible patients with knee osteoarthritis were randomly allocated into two groups. (irct20121106...

Partial thickness rotator cuff tears (PTRCTs) are a common pathology among shoulder disorders in people over 50 years.Treatment of PTRCTs remains controversial. Most studies on the treatment of PTRCTs have explained surgical techniquesor outcomes; few studies have centralized on the conservative and new management of PTRCTs, like treatmentwith Platelet-rich plasma (PRP). These case series study...

background platelet rich plasma is known for its hemostatic, adhesive and healing properties in view of the multiple growth factors released from the platelets to the site of wound. the primary objective of this study was to use autologous platelet rich plasma (prp) in wound beds for anchorage of skin grafts instead of conventional methods like sutures, staplers or glue. methods in a single cen...

BACKGROUND It is still not clear whether native or platelet count adjusted platelet rich plasma (PRP) should be used for platelet aggregation measurements. AIM To evaluate the necessity of using adjusted PRP in platelet function testing. METHODS Platelet aggregation with native PRP and adjusted PRP (platelet count: 250/nl, obtained by diluting native PRP with platelet poor plasma) was perfo...

BACKGROUND Wound healing is a complex and dynamic process following damage in tissue structures. Due to extensive skin damage caused by burn injuries, this study determined the role of human adult peripheral and umbilical cord blood platelet-rich plasma on proliferation and migration in human skin fibroblasts. METHODS Platelet-rich plasma (5, 10, 15, 20 and 50% PRP) from human umbilica...