a topoframe, denoted by $l_{ tau}$,  is a pair $(l, tau)$ consisting of a frame $l$ and a subframe $ tau $ all of whose elements are complementary elements in$l$. in this paper, we define and study the notions of a$tau $-real-continuous function on a frame $l$ and the set of realcontinuous functions $mathcal{r}l_tau $ as an $f$-ring.we show that $mathcal{r}l_{ tau}$is actually a generalization ...

Dysfunction and accumulation of the microtubule-associated human Tau (hTau) protein into intraneuronal aggregates is observed in many neurodegenerative disorders including Alzheimer's disease (AD). Reversible lysine acetylation has recently emerged as a post-translational modification that may play an important role in the modulation of hTau pathology. Acetylated hTau species have been observed...

It has been over a quarter century since the discovery in the mid-1980s that the paired helical filaments of neurofibrillary tangles were made up of abnormally hyperphosphorylated tau. A decade earlier tau had been first isolated from porcine brain as a heat stable protein essential for microtubule assembly. The following years clearly established tau as a microtubule-associated protein that un...

The two pathological hallmarks of Alzheimer's disease, amyloid plaques and neurofibrillary tangles, involve two apparently unrelated proteins, the amyloid precursor protein (APP) and Tau. Although it is known that aberrant processing of APP is associated with Alzheimer's disease, the definitive role of APP in neurons is not yet clear. Tau regulates microtubule stabilization and assembly in axon...

We derive the gravitational energy-momentum pseudo-tensor $\tau^\mu_{\phantom{\mu}\nu}$ in both Palatini and metric approaches to $f(R)$ gravity. then obtain related cosmological energy density. Considering a flat Friedmann-Lema\^itre-Robertson-Walker spacetime, density complex of matter gravitation vanishes approach, but results non-vanishing formalism. This feature could be relevant order phy...

The search for the Higgs boson is one of the main goals of the Large Hadron Collider experiments. Both in the Standard Model (SM) and in its minimal supersymmetric extensions (MSSM), one or several new bosons are expected as manifestations of the Higgs field. The tau lepton will be essential for Higgs(es) discovery. In fact, both in SM and in the MSSM, the Higgs boson(s) decaying into tau-pairs...

Alzheimer's disease (AD) is characterised by the aggregation of two quite different proteins, namely, amyloid-beta (Aβ), which forms extracellular plaques, and tau, the main component of cytoplasmic neurofibrillary tangles. The amyloid hypothesis proposes that Aβ plaques precede tangle formation but there is still much controversy concerning the order of events and the linkage between Aβ and ta...

Let $A$ be a Banach ternary algebra over a scalar field $Bbb R$ or $Bbb C$ and $X$ be a ternary Banach $A$--module. Let $sigma,tau$ and $xi$ be linear mappings on $A$, a linear mapping $D:(A,[~]_A)to (X,[~]_X)$ is called a Lie ternary $(sigma,tau,xi)$--derivation, if $$D([a,b,c])=[[D(a)bc]_X]_{(sigma,tau,xi)}-[[D(c)ba]_X]_{(sigma,tau,xi)}$$ for all $a,b,cin A$, where $[abc]_{(sigma,tau,xi)}=ata...