BACKGROUND The risk of psoriasis in patients with breast cancer is largely unknown, as available evidence is limited to case findings. We systematically examined the incidence and risk factors of psoriasis in patients with breast cancer. METHODS A Swedish nationwide cohort of 56,235 breast cancer patients (2001-2012) was compared to 280,854 matched reference individuals from the general popul...

Psoriasis vulgaris is a chronic, immune-mediated systemic disease that affectŝ7.5 million people in the US. It can be treated with many therapies, often in combination, which include topicals, phototherapy, oral systemics, and biologics. Biologic agents target specific components of the immune system involved in the pathogenesis of psoriasis including TNF-alpha, IL-12, IL-17, and IL-23. The bio...

Pemphigus foliaceus is a chronic autoimmune disease of the skin, clinically characterized by scaly and crusty cutaneous erosions involving the seborrheic areas. The patient can eventually become erythrodermic. There are reports of atypical cases of pemphigus foliaceus with pustules and neutrophils, and clinical differentiation from generalized pustular psoriasis of von Zumbusch is difficult. We...

in order to study the prevalence of psoriatic arthritis in imam reza hospital and determine the effects of factors like age, sex, familial history, type of skin involvement, nail involvement and duration of disease on psoriatic arthritis, 300 psoriatic patients over a period of 4 years were admitted and examined in the department of dermatology and rheumatology in imam reza teaching hospital, (...

Introduction and objective: Psoriasis is a chronic, recurrent, and common inflammatory skin disease, characterized by skin and nail involvements. Onychomycosis is a common disease of the nails. The relationship between psoriasis and onychomycosis is ambiguous. We studied this relationship in psoriasis patients with any nail involvement. Materials and methods: The nail specimens were prepared by...

BACKGROUND: The main vector of psoriasis therapy is suppression proliferative activity keratinocytes, normalization their differentiation, neutralization immune inflammation in the dermis and cytokine balance.
 AIM: study was to efficacy tolerability an IL-17A inhibitor (secukinumab) as monotherapy combination with methotrexate patients moderate severe vulgaris.
 MATERIALS AND METHODS...