نتایج جستجو برای: pulmonary alveolar microlithiasis

تعداد نتایج: 267982  

Journal: :The Journal of Association of Chest Physicians 2019

2017
Alexandros Stamatopoulos Davide Patrini Sofoklis Mitsos Reena Khiroya Elaine Borg Martin Hayward David Lawrence Nikolaos Panagiotopoulos

Pulmonary alveolar microlithiasis (PAM) is an uncommon genetic disorder associated with alveolar cell injury. This injury is caused in most cases by inactivating mutations in SLC34A2 gene, which is responsible for the production of a sodium-dependent phosphate co-transporter. The dysfunction or deficiency of this transporter leads to the aggregation of local phosphate intra-alveolarly and forma...

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