نتایج جستجو برای: pulmonary hypertension
تعداد نتایج: 349238 فیلتر نتایج به سال:
Vitamin K antagonists are advised in pulmonary arterial hypertension patients despite a lack of safety data. We reviewed major bleeding in three classes of pulmonary hypertension patients, all receiving vitamin K antagonists. Bleeding event rates were 5.4 per 100 patient-years for patients with idiopathic pulmonary arterial hypertension, 19 per 100 patient-years for connective tissue disease re...
Background: Chronic Thromboembolic Pulmonary Hypertension (CTEPH) results from the obstruction of predominantly major pulmonary vessels by organized blood clots and is one of the causes of pulmonary hypertension. The disease is still underdiagnosed and the true prevalence is not clear. The objective of this study was to determine the clinical characteristics and current management of patients w...
Pulmonary hypertension is commonly encountered in the intensive care unit (ICU). Although new therapies for pulmonary hypertension have emerged in recent years, the management of critically ill patients with hemodynamically significant pulmonary hypertension remains challenging. Patients with moderate to severe pulmonary hypertension can deteriorate rapidly and are unlikely to survive efforts a...
The effect of pulmonary venous hypertension (PVH) on the pulmonary circulation is extraordinarily variable, ranging from no impact on pulmonary vascular resistance (PVR) to a marked increase. The reasons for this are unknown. Both acutely reversible pulmonary vasoconstriction and pathological remodeling (especially medial hypertrophy and intimal hyperplasia) account for increased PVR when prese...
POEMS syndrome is a rare clonal plasma cell disease. Patients with POEMS syndrome are at risk of developing pulmonary hypertension, but the data on its incidence and impact on outcome are limited. We reviewed records of 154 POEMS syndrome patients with complete duplex echocardiography data for estimation of pulmonary artery systolic pressure (sPAP) at the time of diagnosis. Forty-two (27%) of 1...
IN 1998, the World Health Organization sponsored a symposium on pulmonary hypertension at which a new, more clinically useful classification system was adopted.§ Traditionally, pulmonary hypertension had been classified as being primary or secondary. The classification proposed at the World Health Organization symposium divides pulmonary hypertension into five distinct categories (table 1): (1)...
The inherited hemoglobin disorders sickle cell disease and thalassemia are the most common monogenetic disorders worldwide. Pulmonary hypertension is one of the leading causes of morbidity and mortality in adult patients with sickle cell disease and thalassemia, and hemolytic disorders are potentially among the most common causes of pulmonary hypertension. The pathogenesis of pulmonary hyperten...
The hypothesis that chronic thromboembolic pulmonary hypertension results from unresolved pulmonary embolism has strongly influenced the diagnosis and management of this disease since the 1960s. However, it is nearly impossible to induce chronic pulmonary hypertension in any animal species by means of repeated embolization of thrombotic material. The haemodynamic effects of thrombotic pulmonary...
thrombophilia increases the incidence of pulmonary thrombosis significantly. various hereditary and acquired factors are known for thromboembolism. the hereditary factors are two common genetic autosomal mutations including factor v leidan mutation and prothrombin gene mutation. a descriptive- analytical design was conducted on 60 patients with thromboembolism who met the inclusion criteria. tw...
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