BACKGROUND AND OBJECTIVES Pulsed dye laser (PDL) is the most effective treatment for port wine stain (PWS) birthmarks. However, regeneration and revascularization of photocoagulated blood vessels may result in poor therapeutic outcome. We have recently shown that rapamycin (RPM), an angiogenesis inhibitor, can reduce the regeneration and revascularization of photocoagulated blood vessels. Herei...

BACKGROUND Laser treatment of childhood hemangiomas remains controversial. Previous studies have used outdated technology, resulting in a potential overrepresentation of adverse outcomes. OBJECTIVE To evaluate outcomes of hemangiomas treated with the most current laser technology. METHODS A retrospective chart analysis of 90 patients with a median age of 3.0 months and a total of 105 hemang...

To analyze the clinical characteristics and treatment outcomes of vascular anomalies, and determine which therapy is safe and effective. The data of vascular anomalies pediatric patients who arrived at Beijing children's Hospital from January 2001 to December 2014 were analyzed retrospectively, including the influence of gender, age, clinical manifestation, diagnosis, treatment options, and out...

BACKGROUND Despite the proven effectiveness of the 595-nm pulsed dye laser (PDL) in treating superficial infantile hemangiomas, many physicians are reluctant to treat such lesions involving the eyelid. OBJECTIVE To examine the safety and efficacy of the 595-nm PDL for the treatment of superficial infantile hemangiomas of the eyelid. MATERIALS & METHODS Records were reviewed for patients with ...

Introduction Melasma and postinflammatory hyperpigmentation (PIH) are conditions commonly encountered by dermatologists, they often distressing to patients. While PIH can improve with time once the inflammatory process is controlled, melasma a condition that requires prolonged treatment maintenance. There numerous options, ranging from UV protection topical therapies (such as hydroquinone), mor...

BACKGROUND AND OBJECTIVE In dermatology, the pulsed dye laser (PDL) is the therapeutic instrument of choice for treating most superficial cutaneous vascular lesions. In addition, clinical experience over the last decade allowed us to treat patients with an ever increasing number of non-vascular indications. The purpose of this report is to summarize and critically appraise the scientific eviden...

The exact reason for the effectiveness of pulsed light at a wavelength of 585–595 nm of PDL in the treatment of CLE lesions is unclear. With laser therapy, the applied light is monochromatic, and there is strong evidence that the induced pathogenic mechanisms are different from those caused by irradiation over an ultraviolet spectrum. The suggested working mechanism of PDL (selective phototherm...

Editor Angiokeratomas are rare vascular lesions with secondary verrucous epidermal changes. The exact pathogenesis is unknown, although genetic factors, pregnancy, chilblains, trauma and tissue asphyxia are known causal factors. We report for the first time on the successful treatment of ‘solitary and multiple papular’ type angiokeratomas of the lower extremities with a synchronized dual wavele...

5. Cliff S, Felix RH, Singh L, Harland CC. The successful treatment of lupus pernio with the flashlamp pulsed dye laser. J Cutan Laser Ther. 1999;1:49--52. 6. Roos S, Raulin C, Ockenfels HM, Karsai S. Successful treatment of cutaneous sarcoidosis lesions with the flashlamp pumped pulsed dye laser: a case report. Dermatol Surg. 2009;35:1139--40. 7. O’Donoghue NB, Barlow RJ. Laser remodelling of ...

BACKGROUND This study was performed to assess the photothermal response of highly focused laser energy using infrared thermal imaging instrument to detect and assess the actual temperature distribution during flash lamp pumped pulsed dye laser (FLPPDL) treatment for port wine stain (PWS) patients and avoiding its complications. METHODS A retrospective review of 40 patients with PWS birthmark ...