Pyoderma gangrenosum is a rare non infectious neutrophilic dermatosis commonly associated with underlying systemic disease. Many treatment regimens have been reported. Herein, we report a case of refractory pyoderma gangrenosum with good response to combination of cyclosporine and mycophenolate mofetil.

BACKGROUND Acute rheumatic fever is a major cause of heart disease in Aboriginal Australians. The epidemiology differs from that observed in regions with temperate climates; streptococcal pharyngitis is reportedly rare, and pyoderma is highly prevalent. A link between pyoderma and acute rheumatic fever has been proposed but is yet to be proven. Group C beta-hemolytic streptococci and group G be...

Pyoderma gangrenosum occurrence in a familial pattern is extremely rare. We report pyoderma gangrenosum in two Tunisian siblings with onset respectively at 28 and 26 years old. The initial lesion was a pustule that breaks down to form an ulcer with an erythematous border. Treatment with oral corticosteroids induced an excellent clinical response. This familial clustering suggests a possible gen...

Pyoderma gangrenosum is an uncommon, destructive, cutaneous ulceration which presents as ulcerative, pustular, bulluous and vegetative forms, the ulcerative forms being more common. We present the case of 41-year-old woman with Crohn's disease who presented with a rather unusual form of pyoderma gangrenosum, aseptic cutaneous abscess. It was initially misdiagnosed as a fistulous tract in the ab...

Pyoderma gangrenosum is an uncommon ulcerative cutaneous dermatosis associated with a variety of systemic diseases including inflammatory bowel disease, arthritis, hematological malignancies, hepatitis and acquired immunodeficiency syndrome (AIDS). The pathogenesis of pyoderma gangrenosum remains unknown. Its diagnosis is usually based on clinical evidence and confirmed through a process of eli...

PG: pyoderma gangrenosum TNF: tumor necrosis factor INTRODUCTION Pyoderma gangrenosum (PG) is a neutrophilic dermatosis with an important inflammatory component that usually presents as a nonhealing ulcer. This cutaneous disorder has been associated with several systemic conditions including inflammatory bowel disease. Treatment options for PG in pregnancy are limited. We present a case of pyod...

BACKGROUND: Primary pyodermas are common in children. Environmental factors like overcrowding, hygiene, poverty, malnutrition etc. have been implicated to predispose to pyoderma, especially in children. OBJECTIVES: 1.To evaluate the epidemiological spectrum of pyoderma in children,2.To assess the role of predisposing factors 3.To determine the clinical profile of the cases and 4. To isolate the...

75 n INTRODUCTION Recurrent bacterial pyoderma in dogs is frequently a source of frustration for both pet owners and clinicians. Although many canine patients with bacterial pyoderma respond appropriately and completely to initial therapeutic management, many relapse. When diagnostic tests fail to reveal an underlying cause of recurrent superficial pyoderma (e.g., allergic disease, hypothyroidi...