Exercise-induced muscle oxidative stress may be involved in the myopathy associated with chronic obstructive pulmonary disease (COPD). This study was designed to look at whether local exercise induces muscle oxidative stress and whether this may be associated with the reduced muscle endurance in COPD. Quadriceps endurance was measured in 12 patients with COPD (FEV1 = 0.96 [[plusmn]] 0.14 SEM) a...

current research attempted to compare the effect of 10-day oral supplementation with saffron and indomethacin in the prevention of delayed onset muscle soreness (doms). thirty-nine healthy and inactive male students divided into three groups: saffron (300 mg), indomethacin (75 mg), and control groups. muscle soreness protocol performed with 80% of 1rm in four sessions and each session had 20 re...

The quadriceps femoris is traditionally described as a muscle group composed of the rectus femoris and the three vasti. However, clinical experience and investigations of anatomical specimens are not consistent with the textbook description. We have found a second tensor-like muscle between the vastus lateralis (VL) and the vastus intermedius (VI), hereafter named the tensor VI (TVI). The aim o...

RATIONALE Strength training and neuromuscular electrical stimulation (NMES) improve lower-limb muscle function in dyspnoeic individuals with chronic obstructive pulmonary disease (COPD). However, high-frequency NMES (HF-NMES) and strength training have never been compared head-to-head; and effects of low-frequency NMES (LF-NMES) have never been studied in COPD. Therefore, the optimal training m...

To elucidate the potential limitations on maximal human quadriceps O2 capacity, six subjects trained (T) one quadriceps on the single-legged knee extensor ergometer (1 h/day at 70% maximum workload for 5 days/wk), while their contralateral quadriceps remained untrained (UT). Following 5 wk of training, subjects underwent incremental knee extensor tests under normoxic (inspired O2 fraction = 21%...

BACKGROUND Systemic proinflammatory cytokines and oxidative stress have been described in association with peripheral muscle wasting and weakness of patients with severe chronic obstructive pulmonary disease (COPD), but their expression in skeletal muscle is unknown. The objectives of the present study were to determine muscle protein levels of selected cytokines in patients with COPD and to st...

background: previous studies have shown detrimental effects of muscle fatigue on balance. also they have reported the effects of kinesio taping (kt) on postural control, joint support, and muscle function. however, no studies have been conducted so far to assess the immediate effects of kt after local muscle fatigue on balance. therefore, the aim of this study was to determine whether kt improv...

We examined the size of the four muscles of the quadriceps femoris in young and old men and women to assess whether the vastus lateralis is an appropriate surrogate for the quadriceps femoris in human studies of aging skeletal muscle. Ten young (24 +/- 2 yr) and ten old (79 +/- 7 yr) sedentary individuals underwent magnetic resonance imaging of the quadriceps femoris after 60 min of supine rest...

Purpose: An appropriate activity of the knee agonist -antagonist muscles is important to resist against abnormal abduction-adduction moments loads around knee joint and reduce the risk of knee injuries. Exercise training has been commonly used as an intervention to improve neuromuscular activity within the synergic and/or agonist-antagonist muscles. However, maximizing the effectiveness of exer...

STUDY OBJECTIVES The purpose of this study was to compare the effects of endurance training only to endurance plus strength (combined) training in a randomized trial of patients with COPD. METHODS Twenty-four patients completed the study: 11 patients in the combined training group (FEV(1) 45 +/- 5% predicted), and 13 patients in the endurance training group (FEV(1) 40 +/- 4% predicted) [mean ...