نتایج جستجو برای: quality adjusted life years
تعداد نتایج: 2194325 فیلتر نتایج به سال:
Clinical trials often employ many different endpoints to evaluate the benefits and risks associated with treatment. These endpoints, however, may not always align with one another. In oncology studies, for instance, a more efficacious treatment, which prolongs survival, may also be associated with greater toxicity, which decreases quality of life. Quality-adjusted survival analysis (QASA) provi...
BACKGROUND Excessive alcohol use increases risks of chronic diseases such as coronary heart disease and several types of cancer, with associated losses of quality of life and life-years. Alcohol taxes can be considered as a public health instrument as they are known to be able to decrease alcohol consumption. In this paper, we estimate the cost-effectiveness of an alcohol tax increase for the e...
Cost-effectiveness of a vaccine to prevent herpes zoster and postherpetic neuralgia in older adults.
BACKGROUND A vaccine to prevent herpes zoster was recently approved by the United States Food and Drug Administration. We sought to determine the cost-effectiveness of this vaccine for different age groups. METHODS We constructed a cost-effectiveness model, based on the Shingles Prevention Study, to compare varicella zoster vaccination with usual care for healthy adults aged >60 years. Outcom...
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